Cerebral metastases from lung carcinoma: neurological and CT correlation. Work in progress.

Tarver, RD; Richmond, B D; Klatte, Eugene C.

doi:10.1148/radiology.153.3.6093189

Cited by 59 publications

(22 citation statements)

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“…CT of the brain has a well-documented accuracy in detecting metastatic tumors and has been described as being of value in the staging of patients who were free of neurologic symptoms [11,20,24]. Recently, magnetic resonance imaging (MRI) has also started to be used for diagnosing brain tumors, and contrast-enhanced MRI has been demonstrated to be very sensitive to small lesions and documented to have a higher sensitivity than CT [19,23].…”

Section: Discussionmentioning

confidence: 99%

Is a Diagnostic CT of the Brain Indicated in Patients with Choroidal Metastases Before Radiotherapy?

Bottke

Wiegel

Kreusel³

et al. 2005

Strahlenther Onkol

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A CCT is indicated at the diagnosis of choroidal metastases for screening of synchronous brain metastases. The incidence is about 25%, and the diagnosis of brain metastases results in a different target volume: the whole brain including the posterior parts of the eyes compared to the posterior parts of the eyes alone. Therefore, the risk of late side effects could be reduced compared with an additional later radiotherapy of the whole brain with partly overlapping fields.

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Section: Discussionmentioning

confidence: 99%

Is a Diagnostic CT of the Brain Indicated in Patients with Choroidal Metastases Before Radiotherapy?

Bottke

Wiegel

Kreusel³

et al. 2005

Strahlenther Onkol

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“…The appearance on CT scans of the brain is that of a low-density mass with surrounding ring enhancement at the junction of the grey and white matter. 9 Tuberous sclerosis is a neurocutaneous disorder characterized by childhood epilepsy, intellectual impairment and dermatological manifestations. CT scans of the head typically reveal subependymal nodules or cortical "tubers" in the brain.…”

Section: T He Correct Diagnosis Is Hypoparathyroidism (A)mentioning

confidence: 99%

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Deady

Wallace

Siu

2007

CJEM

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T he correct diagnosis is hypoparathyroidism (a).The CT scan of the head demonstrates diffuse intracranial calcifications, and on laboratory investigation the patient was found to be severely hypocalcemic (serum calcium was 1.33 mmol/L; normal range 2.10-2.60 mmol/L). His phosphorous was elevated (2.1 mmol/L; normal range 0.8-1.5 mmol/L) and, of course, his parathyroid hormone level (PTH) was low (0.4 pmol/L; normal range 1.5-7.6 pmol/L).Intracranial calcification, especially in the basal ganglia, is a recognized complication of longstanding hypocalcemia due to hypoparathyroidism or pseudohypoparathyroidism.1-8 Diffuse calcification of the cerebral cortex, subcortical matter, basal ganglia, thalamus and cerebellum are easily identifiable on the CT scan of this patient's brain ( Fig. 1 and Fig. 2).Metastatic carcinoma of the brain most commonly originates from a primary bronchogenic carcinoma. The appearance on CT scans of the brain is that of a low-density mass with surrounding ring enhancement at the junction of the grey and white matter. Tuberous sclerosis is a neurocutaneous disorder characterized by childhood epilepsy, intellectual impairment and dermatological manifestations. CT scans of the head typically reveal subependymal nodules or cortical "tubers" in the brain. 10The appearance of blood due to subarachnoid hemorrhage on CT scan is dependent upon the location of the aneurysm within the circle of Willis and the delay between

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“…Brain CT is usually only performed when symptoms are present or in aggressive tumours. The chance of brain metastasis even in patients with normal neurological examination increases when the tumour is more aggressive [98].…”

Section: Evaluation Of Distant Metastasis: the M Factormentioning

confidence: 99%

Computed tomography in staging for lung cancer

Verschakelen¹,

Bogaert²,

Wever³

2002

Eur Respir J

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Computed tomography (CT) provides the most detailed imaging information, hence it is generally used as a routine imaging procedure in the tumour, node, metastasis (TNM)-staging of patients with lung cancer. However, despite the continuously ongoing process of improvement in CT scanning in which today9s CT scanners combine fast acquisition, fast data reconstruction and high detail, the technique has important limitations.CT can, in some cases, very accurately show tumour extent within, and predict spread beyond the lung. However, the question of whether the tumour has invaded the chest wall or the mediastinum and, if so, whether it is still potentially surgically curable often remains unanswered. In addition, the only sign for predicting lymph node involvement using CT is enlargement. Many studies have shown that this sign is not very reliable. CT is also, with success, being used to evaluate distant metastases although other techniques such as ultrasound and magnetic resonance imaging can have similar or higher accuracies.Despite these well-known limitations, computed tomography will most likely stay the routine imaging procedure for determining resectability and for assessing intra-and extrathoracic spread of lung cancer. The improvement in technology will probably result a better T-staging. The role of computed tomography in nodal staging remains important. It offers the surgeon a road map of the lymph nodes and guides towards the nodes that need biopsy. Combining computed tomography with positron emission tomography, when it becomes more widely available, will add functional images to the detail of computed tomography and will not only improve nodal staging but will probably also allow a better evaluation of distant metastasis and reduce the number of unnecessary interventional procedures.

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Cerebral metastases from lung carcinoma: neurological and CT correlation. Work in progress.

Cited by 59 publications

References 0 publications

Is a Diagnostic CT of the Brain Indicated in Patients with Choroidal Metastases Before Radiotherapy?

Is a Diagnostic CT of the Brain Indicated in Patients with Choroidal Metastases Before Radiotherapy?

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Computed tomography in staging for lung cancer

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