Cerebral oxygenation during skin-to-skin care in preterm infants not receiving respiratory support

Abstract

This trial is linked to Australian New Zealand Clinical Trials Registry: identifier 12616000240448. It was registered pre-results.

The effect of skin‐to‐skin care on cerebral oxygenation during nasogastric feeding of preterm infants

“…Furthermore, SpO 2 was lower during‐feed in SSC (1.5%) compared within the incubator. This might be explained by the lower SpO 2 values observed during SSC in the original studies (−0.5% and −1.1%) which are unlikely to be clinically important.…”

“…Eighty infants were recruited between September 2015 and September 2016 for the two primary studies . Of the 80 infants, 39 had their pre‐/during‐ and postfeed period in one of the two incubator periods and 20 infants were fed both during incubator and SSC.…”

“…Two prospective, non‐inferiority, crossover trials were performed at the Royal Women's Hospital in Melbourne, Australia . Written informed prospective parental consent was obtained, and both studies were approved by the hospital human research and ethics committee.…”

“…Written informed prospective parental consent was obtained, and both studies were approved by the hospital human research and ethics committee. Primary outcome results have been presented elsewhere . Data collected during these studies were used to compare rStO 2 and other physiological parameters in preterm infants (<33 weeks' gestation) before, during and after SSC (Fig.…”

“…Bradycardic events were defined as HR < 100 beats per minute (bpm) for > five seconds, and hypoxic events were defined as SpO 2 < 80% for > five seconds. ‘Cerebral hypoxia’ was defined as rStO 2 < 55% and ‘cerebral hyperoxia' as rStO 2 > 85% . Cerebral fractional tissue oxygen extraction (cFTOE) is a measure of cerebral oxygen delivery and consumption.…”