Cerebral Palsy: Sport and Exercise Considerations

Toldi, James; Escobar, Joseph; Brown, Austin

doi:10.1249/jsr.0000000000000798

Cited by 14 publications

(5 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the absence of research evidence, some clinicians and researchers have vastly underestimated the physical capabilities of this group. One recent review stated that people at GMFCS IV and V ‘…will struggle performing structured exercise programmes’ and ‘are unable to perform activities greater than 1.0 MET’ 30. Note that 1.0 METs is the energy expended during quiet sitting 31.…”

Section: Discussionmentioning

confidence: 99%

The power of Para sport: the effect of performance-focused swimming training on motor function in adolescents with cerebral palsy and high support needs (GMFCS IV) – a single-case experimental design with 30-month follow-up

Dutia,

Connick,

Beckman

et al. 2024

Br J Sports Med

View full text Add to dashboard Cite

ObjectiveThis study aims to evaluate the effect of a performance-focused swimming programme on motor function in previously untrained adolescents with cerebral palsy and high support needs (CPHSN) and to determine whether the motor decline typical of adolescents with CPHSN occurred in these swimmers.MethodsA Multiple-Baseline, Single-Case Experimental Design (MB-SCED) study comprising five phases and a 30-month follow-up was conducted. Participants were two males and one female, all aged 15 years, untrained and with CPHSN. The intervention was a 46-month swimming training programme, focused exclusively on improving performance. Outcomes were swim performance (velocity); training load (rating of perceived exertion min/week; swim distance/week) and Gross Motor Function Measure-66-Item Set (GMFM-66). MB-SCED data were analysed using interrupted time-series simulation analysis. Motor function over 46 months was modelled (generalised additive model) using GMFM-66 scores and compared with a model of predicted motor decline.ResultsImprovements in GMFM-66 scores in response to training were significant (p<0.001), and two periods of training withdrawal each resulted in significant motor decline (p≤0.001). Participant motor function remained above baseline levels for the study duration, and, importantly, participants did not experience the motor decline typical of other adolescents with CPHSN. Weekly training volumes were also commensurate with WHO recommended physical activity levels.ConclusionsResults suggest that adolescents with CPHSN who meet physical activity guidelines through participation in competitive swimming may prevent motor decline. However, this population is clinically complex, and in order to permit safe, effective participation in competitive sport, priority should be placed on the development of programmes delivered by skilled multiprofessional teams.Trial registration numberACTRN12616000326493.

show abstract

Section: Discussionmentioning

confidence: 99%

The power of Para sport: the effect of performance-focused swimming training on motor function in adolescents with cerebral palsy and high support needs (GMFCS IV) – a single-case experimental design with 30-month follow-up

Dutia,

Connick,

Beckman

et al. 2024

Br J Sports Med

View full text Add to dashboard Cite

show abstract

“…A more recent study raised concerns about the frequency of injections, showing no complete recovery at 6 months [ 25 ], and suggested that longer intervals between reinjections are preferable. The possibility of counteracting atrophy with available drugs or accelerating recovery through the use of other treatments such as exercise or increased physiotherapy might fasten recovery after BoNT treatment [ 85 , 86 ].…”

Section: Discussionmentioning

confidence: 99%

Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions

Costamagna,

Bastianini,

Corvelyn

et al. 2023

Cells

View full text Add to dashboard Cite

Botulinum neurotoxin type-A (BoNT) injections are commonly used as spasticity treatment in cerebral palsy (CP). Despite improved clinical outcomes, concerns regarding harmful effects on muscle morphology have been raised, and the BoNT effect on muscle stem cells remains not well defined. This study aims at clarifying the impact of BoNT on growing muscles (1) by analyzing the in vitro effect of BoNT on satellite cell (SC)-derived myoblasts and fibroblasts obtained from medial gastrocnemius microbiopsies collected in young BoNT-naïve children (t0) compared to age ranged typically developing children; (2) by following the effect of in vivo BoNT administration on these cells obtained from the same children with CP at 3 (t1) and 6 (t2) months post BoNT; (3) by determining the direct effect of a single and repeated in vitro BoNT treatment on neuromuscular junctions (NMJs) differentiated from hiPSCs. In vitro BoNT did not affect myogenic differentiation or collagen production. The fusion index significantly decreased in CP at t2 compared to t0. In NMJ cocultures, BoNT treatment caused axonal swelling and fragmentation. Repeated treatments impaired the autophagic–lysosomal system. Further studies are warranted to understand the long-term and collateral effects of BoNT in the muscles of children with CP.

show abstract

“…Recommendations. The American College of Sports Medicine provides the following recommendations for people living with cerebral palsy [17]. 1.…”

Section: Things To Consider Before Starting To Exercisementioning

confidence: 99%

Physical Activity for Individuals with Cerebral Palsy

Law

Pennington

2021

Int. J. Phys. Educ. Fit. Sports

View full text Add to dashboard Cite

Despite the fact that cerebral palsy affects the balance, coordination, muscles, and movements of individuals, adaptive sports can be used to help individuals with cerebral palsy stay physically active. High-quality physical education and movement opportunities can integrate children with cerebral palsy into movement programing, as to enable children with cerebral palsy to achieve goals related to cognitive skills associated with exploring physical health, maintaining physical health, as well as affective values towards physical health, movement, play, and general wellbeing. Cerebral palsy has not prevented some people from being athletes who have managed to compete on the international stage. Sports is one way to encourage people with cerebral palsy to socialize, be fit, stay healthy, and, most importantly, have fun. Enjoyment of physical activity can improve the self-efficacy of individuals with cerebral Palsy. It can motivate them to override pain and sustain their participation. This article details the considerations, recommendations, safety concerns, and facilitation protocols for individuals with cerebral palsy participating in adapted sport.

show abstract

Cerebral Palsy: Sport and Exercise Considerations

Cited by 14 publications

References 41 publications

The power of Para sport: the effect of performance-focused swimming training on motor function in adolescents with cerebral palsy and high support needs (GMFCS IV) – a single-case experimental design with 30-month follow-up

The power of Para sport: the effect of performance-focused swimming training on motor function in adolescents with cerebral palsy and high support needs (GMFCS IV) – a single-case experimental design with 30-month follow-up

Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions

Physical Activity for Individuals with Cerebral Palsy

Contact Info

Product

Resources

About