1994
DOI: 10.1056/nejm199412013312204
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Cerebral Syphilitic Gumma Confirmed by the Polymerase Chain Reaction in a Man with Human Immunodeficiency Virus Infection

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Cited by 66 publications
(27 citation statements)
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“…These genes include tpf-1 (14), the BMP gene (10,14,22), the tmpA and tmpB genes (7,8), and the 47-kDa protein gene (2,6,11,15,18,20); most recently RT-PCR has been performed by using the 16S rRNA (3). Most functions of the target genes are unknown or poorly characterized (e.g., those of tpf-1, the BMP gene, tmp, and the 47-kDa protein gene).…”
Section: Discussionmentioning
confidence: 99%
“…These genes include tpf-1 (14), the BMP gene (10,14,22), the tmpA and tmpB genes (7,8), and the 47-kDa protein gene (2,6,11,15,18,20); most recently RT-PCR has been performed by using the 16S rRNA (3). Most functions of the target genes are unknown or poorly characterized (e.g., those of tpf-1, the BMP gene, tmp, and the 47-kDa protein gene).…”
Section: Discussionmentioning
confidence: 99%
“…T. pallidum DNA also can be detected in skeletal bones and various body fluids, including serum (2), cerebrospinal fluid, and urine (5,14,16,18,37). T. pallidum DNA also has been detected in specimens from placenta (15), gastric lesions (22), and neurons (21).…”
mentioning
confidence: 99%
“…Polymerase chain reaction assays have been useful in detecting T. pallidum in lesions of late secondary syphilis and tertiary syphilis, including syphilitic gummas [57,58], and in gastric lesions [59]. They have also been used to detect T. pallidum in cerebrospinal fluid [60,61] and to diagnose congenital syphilis [61].…”
Section: Syphilismentioning
confidence: 98%