Cerebral vasculitis in a teenager with Goodpasture's syndrome

Gittins, Nicola; Basu, Anna; Eyre, J A; Gholkar, A; Moghal, Nadeem

doi:10.1093/ndt/gfh448

Cited by 23 publications

(10 citation statements)

References 6 publications

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“…All three of these patients presented with recurrent seizures, with or without hemoptysis. The brain MRI findings of these patients showed diffusely distributed lacunar infarct (8) or multifocal cortical ischemia in the occipital and parietal lobes (9, 10). These findings are similar to those presented by our patient.…”

Section: Discussionmentioning

confidence: 97%

“…Particularly, CNS vasculitis associated with Goodpasture's syndrome is extremely rare, with only three cases of the disease having been reported in the literature (8-10). All three of these patients presented with recurrent seizures, with or without hemoptysis.…”

Section: Discussionmentioning

confidence: 99%

“…Central nervous system (CNS) manifestations in Goodpasture's syndrome are extremely rare, with only a few cases having been reported in the literature (8-10). Therefore, we present our imaging findings of CNS vasculitis associated with Goodpasture's syndrome, together with a review of the relevant literature.…”

mentioning

confidence: 99%

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Imaging Findings of Central Nervous System Vasculitis Associated with Goodpasture's Syndrome: a Case Report

et al. 2007

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Glomerulonephritis and pulmonary hemorrhage are features of Goodpasture's syndrome. Goodpasture's syndrome accompanied with central nervous system (CNS) vasculitis is extremely rare. Herein, we report a rare case of CNS vasculitis associated with Goodpasture's syndrome in a 34-year-old man, who presented with a seizure and sudden onset of right sided weakness. He also had recurrent hemoptysis of one month's duration. Goodpasture's syndrome is histologically diagnosed by intense linear deposits of IgG along the glomerular basement membrane in both renal and lung tissues.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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Imaging Findings of Central Nervous System Vasculitis Associated with Goodpasture's Syndrome: a Case Report

et al. 2007

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“…Only four Goodpasture cases (all without pANCA) with cerebral vasculitis have been previously described. [2][3][4] In all, 15-30%…”

Section: Discussionmentioning

confidence: 99%

Spinal subarachnoid hematomas and cerebral infarctions in Goodpasture's disease

et al. 2010

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“…Central nervous system (CNS) manifestations in GPS are extremely rare, with only a few cases having been reported in the literature (Rydel and Rodby 1998;Garnier et al 2003;Nicola et al 2004). There are some case reports of associated systemic vasculitis with GPS (Kim et al 2007) and cerebral vasculitis in teenagers (Gittins et al 2004).…”

Section: 1mentioning

confidence: 99%