Cerebral Venous Sinus Thrombosis : A Great Masquerader

Mehta, SR; Muthukrishnan, J; Varadarajulu, R; Gupta, Aditya

doi:10.1016/s0377-1237(04)80072-8

Cited by 8 publications

(8 citation statements)

References 5 publications

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“…Alcohol contributes to thrombosis by dehydration, hypercoagulability, and reactive thrombocytosis. [21] Overall, 42 (9.8%) patients were postpartum, which was equal to that reported in most western studies [22,23] and less than 31-86% as reported from a few Asian studies. [24,25] Less cases of postpartum CSVT in this study probably represent better women healthcare.…”

Section: Discussionmentioning

confidence: 67%

Risk factors, clinical profile, and long-term outcome of 428 patients of cerebral sinus venous thrombosis: Insights from Nizam′s Institute Venous Stroke Registry, Hyderabad (India)

Narayan

Kaul

Ravishankar³

et al. 2012

Neurol India

103

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Section: Discussionmentioning

confidence: 67%

Risk factors, clinical profile, and long-term outcome of 428 patients of cerebral sinus venous thrombosis: Insights from Nizam′s Institute Venous Stroke Registry, Hyderabad (India)

Narayan

Kaul

Ravishankar³

et al. 2012

Neurol India

103

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“…In the Armed Forces, previous studies by Kumaravelu et al 17 and Mehta et al, 18 have reported high altitude exposure as a very important provoking factor peculiar to the troops deployed in these areas. The manifestations can be very subtle and protean, requiring a high index of suspicion toward CVT, for doctors working in these regions.…”

Section: [ ( F I G _ 4 ) T D $ F I G ]mentioning

confidence: 95%

A study of clinical, radiological and etiological profile of cerebral venous sinus thrombosis at a tertiary care center

Anadure

Vinny

Sahu

et al. 2018

Medical Journal Armed Forces India

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Background: A prospective, observational study was done at a tertiary care hospital in Western Maharashtra to describe the etiologies, clinical features, diagnosis and prognosis of cerebral venous sinus thrombosis in an Indian population. Methods: 54 patients with clinical and MRI features suggestive of cerebral venous sinus thrombosis (CVST), were studied with detailed clinical evaluation and pro-thrombotic work up. All were followed up monthly for 6 months, to assess the response to therapy and clinical outcomes. Results: The mean age of presentation was 35 years. Headache was the most common presenting symptom (94%) and hemi paresis (22%) was the most common neurological sign. The most common sinus involved was transverse sinus in 77% of cases. In the unprovoked CVST subset (n = 29), elevated factor VIII (72%) and protein C deficiency (24%) were the common prothrombotic states identified. In the provoked CVST subset (n = 18), puerperium (44%) and para-infectious (22%) accounted for majority cases. Idiopathic CVST accounted for 13% (7/54) in this study. A Modified Rankin Scale (MRS) of 0-1 was achieved in 96% of patients at the end of 6 months follow up with no mortality in this study. Conclusion: CVST is an important yet under recognized cause of intracranial hypertension and stroke in young. Clinical presentation is extremely varied and a high index of suspicion is needed. Magnetic Resonance Imaging (MRI) brain with Magnetic Resonance Venography (MRV) is the current diagnostic modality of choice. Elevated factor VIII and puerperium are the common etiologies in an Indian population. Management with anticoagulants is safe and has excellent clinical outcomes.

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“…Although in 25% of cases the etiology remains elusive, the usual risk factors of CVST are meningitis, parameningeal infections, facial and paranasal sinus infections, thrombophilia, antiphospholipid syndrome, homocystinuria, pregnancy, alcoholism, dehydration, malignancies, paroxysmal nocturnal hemoglobinuria, and contraceptive medications [3]. 25% of cases etiology remains elusive [3]. Superior sagittal sinus remains the most common site for thrombus formation (72%), followed by lateral sinus (70%) [3].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Alcohol Intoxication Masquerading Cerebral Venous Sinus Thrombosis

Siddiqui

Tshering²,

Jayasekhar

et al. 2020

EJMED

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Cerebral venous sinus thrombosis remains a diagnostic challenge courtesy to its variable degree of presentation and low level of clinical suspicion. We report a rare case of cerebral venous sinus thrombosis presenting as a complication of alcohol intoxication. Symptoms of cerebral venous sinus thrombosis are likely to remain camouflaged in alcoholics making the task for the clinician more so difficult. Strong suspicion should remain in any alcoholics with persistent neurologic features. A 52-year-old gentleman presenting with delirium, seizure, and a persistent headache was found to have multiple cerebral venous sinus thrombosis. After ruling out all the possible risk factors eventually we came into the conclusion of the role of alcohol inducing this catastrophic condition. He was treated with anticoagulant resulting in prompt resolution of his symptoms. Anti-coagulation was discontinued after 3 months and the patient continues to remain asymptomatic after 6months of regular follow-up.

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Cerebral Venous Sinus Thrombosis : A Great Masquerader

Cited by 8 publications

References 5 publications

Risk factors, clinical profile, and long-term outcome of 428 patients of cerebral sinus venous thrombosis: Insights from Nizam′s Institute Venous Stroke Registry, Hyderabad (India)

Risk factors, clinical profile, and long-term outcome of 428 patients of cerebral sinus venous thrombosis: Insights from Nizam′s Institute Venous Stroke Registry, Hyderabad (India)

A study of clinical, radiological and etiological profile of cerebral venous sinus thrombosis at a tertiary care center

A Rare Case of Alcohol Intoxication Masquerading Cerebral Venous Sinus Thrombosis

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