Cerebrale Krankheiten des Kindesalters in typischen Encephalogrammen

Kruse, Friedrich E.

doi:10.1007/978-3-642-90647-3_4

Cited by 7 publications

(4 citation statements)

References 97 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, we demonstrated that both LS‐CSF volume per weight and TLS‐CSF volume per weight do not decrease drastically with age. Additionally, spinal CSF volume was not as large as previously reported in neonates . Rochette et al also reported that the spinal CSF volume, from the first thoracic vertebra to the caudal end, was 1.97 (0.54) mL/kg in preterm and term neonates, which was similar to the present study.…”

Section: Discussionsupporting

confidence: 90%

“…Additionally, spinal CSF volume was not as large as previously reported in neonates. [6][7][8][9] Rochette et al 10 0.15-0.2 mg/kg for adults. [14][15][16][17] The recommended dose of local anesthetics for spinal anesthesia in neonates was 3-5 times that of adults.…”

Section: Discussionmentioning

confidence: 99%

“…Based on this information, spinal CSF volume can be estimated as more than 5 mL/kg in neonates and 0.375‐0.5 mL/kg in adolescents and adults. However, these reference values were determined in old studies in which the methods used had certain limitations . Cutler et al used isotonic dilution of radioactive iodinated albumin ( 125 I‐albumin) during ventriculo‐lumbar perfusions in 11 patients from ages 5 to 13 and reported a CSF volume of 3.9 (1.1) mL/kg.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, there is not enough evidence to show how spinal CSF volume changes according to weight, height, and age in the pediatric population. Data regarding spinal CSF volume across development comes from old literature; therefore, it is vital to have good, contemporary magnetic resonance (MR) image‐based estimations of CSF volume through the spinal column in neonates, infancy, childhood, and adolescence.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Lumbosacral and thoracolumbosacral cerebrospinal fluid volume changes in neonates, infants, children, and adolescents: A retrospective magnetic resonance imaging study

Jang

Lee

Seo

et al. 2018

Pediatric Anesthesia

View full text Add to dashboard Cite

Summary Background The volume of cerebrospinal fluid can affect the pharmacokinetics and pharmacodynamics of local anesthetics for spinal anesthesia and other intrathecal medications. Aims The objective of this study was to estimate the lumbosacral cerebrospinal fluid volume and thoracolumbosacral cerebrospinal fluid volume using magnetic resonance images in pediatric patients from neonates and infants to adolescents. Methods Spinal magnetic resonance images of 500 pediatric patients (age <18 years) were reviewed. The lumbosacral cerebrospinal fluid volumes of 418 patients and thoracolumbosacral cerebrospinal fluid volumes of 248 patients were measured. The relationship between cerebrospinal fluid volumes and age, height, and weight were evaluated. The lumbosacral and thoracolumbosacral cerebrospinal fluid volumes per weight were calculated to elucidate developmental changes. Results The lumbosacral and thoracolumbosacral cerebrospinal fluid volumes showed linear correlations with height (r2 = 0.730 and r2 = 0.661, respectively), whereas they showed curvilinear correlations with age (r2 = 0.752 and r2 = 0.717, respectively) and weight (r2 = 0.734 and r2 = 0.734, respectively). The mean lumbosacral cerebrospinal fluid volume per weight (mL/kg) was 0.85 (standard deviation [SD]: 0.19, 95% confidence interval [CI]: 0.81‐0.90) in neonates and infants, 0.86 (SD: 0.22, 95% CI: 0.83‐0.89) in toddlers and preschoolers, 0.71 (SD: 0.26, 95% CI: 0.66‐0.76) in schoolers, and 0.54 (SD: 0.20, 95% CI: 0.49‐0.60) in adolescents. The mean thoracolumbosacral cerebrospinal fluid volume per weight (mL/kg) was 1.95 (SD: 0.37, 95% CI: 1.86‐2.04) in neonates and infants, 1.82 (SD: 0.41, 95% CI: 1.75‐1.88) in toddlers and preschoolers, 1.38 (SD: 0.40, 95% CI: 1.23‐1.52) in schoolers, and 0.99 (SD: 0.34, 95% CI: 0.45‐1.53) in adolescents. Conclusion The lumbosacral and thoracolumbosacral cerebrospinal fluid volumes in pediatric patients were much smaller than previously presented values, showing linear correlations with height, and demonstrate curvilinear correlations with age and weight.

show abstract

Section: Discussionsupporting

confidence: 90%