2002
DOI: 10.1046/j.1468-3083.2002.00435.x
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Cerebriform intradermal naevus (a rare form of secondary cutis verticis gyrata)

Abstract: In each individual case the physician must decide whether to do surgery or follow a wait-and-see policy. There is little risk of malignant change of CIN, and surgical excision of such lesions often involves evident mutilation.

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Cited by 19 publications
(28 citation statements)
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“…Hammond and Ransom first described a Cerebriform nevus resembling cutis verticis gyrata in 1937 [8]. Presenting at birth or early life, it is attributed that females are more likely to develop this condition [7].…”
Section: Discussionmentioning
confidence: 99%
“…Hammond and Ransom first described a Cerebriform nevus resembling cutis verticis gyrata in 1937 [8]. Presenting at birth or early life, it is attributed that females are more likely to develop this condition [7].…”
Section: Discussionmentioning
confidence: 99%
“…7 Lesions are normally present at birth as normal-colored or over-pigmented macules that increase in size and stand further proud as the years pass. The lesions gradually begin to take on their brain-like appearance which leads to alopecia in addition to the possibility of itching, bleeding, secondary infections and foul smell, due to bacterial proliferation in the folds.…”
Section: Traumamentioning
confidence: 99%
“…10 Furthermore, although rare, the brain-like lesions can affect other areas and cases have been described where the neck and scrotum were involved as has a case where a malignant peripheral melanoma was associated with a giant melanocytic intradermal nevus. 11,12,13 With relation to size, CIN can vary from 2 x 3 cm to 22.5 x 25 cm 7,14 Diagnosis of CIN is based on clinical findings and confirmed by histopathology. 7 Characteristics of a positive histopathological result are: nevocytes arranged intradermally with a minimal junctional component, possibly affecting superficial parts of the hypodermis; adjacent structures enveloped by nevocytes; loss of the typical arrangement of nests in stretches; a prevalence of type C nevus cells with large areas of neuroid differentiation; irregular arrangement and distribution of intracellular melanin pigment and perivascular nevocyte aggregation.…”
Section: Traumamentioning
confidence: 99%
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“…2 CIN is not associated with systemic diseases, whereas cutis verticis gyrata is usually accompanied by endocrinological or neurological diseases. 1,3 CIN is a potential risk factor for the development of malignant melanoma, and the incidence can rise up to over 10%. 1,4 Due to psychological complications, aesthetic considerations, and the probability of developing malignancies, surgical excision of the lesion is required.…”
Section: Introductionmentioning
confidence: 99%