Certain pesticide-induced carbohydrate metabolic disorders in the serum of freshwater fish Clarias batrachus (Linn.)

Jyothi, B.; Narayan, Gopeshwar

doi:10.1016/s0278-6915(99)00020-4

Cited by 71 publications

(34 citation statements)

References 14 publications

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“…Sublethal concentrations of methamidophos, phorate, and RPR-II seem to increase AcP and ALP in plasma and lower them in the liver tissue of animals (60,68,69). Similar findings have been reported for sub-chronic monocrotophos, methyl parathion, and dimethoate effects on ALP and AcP levels in plasma, but not in the liver, where they also increased (21,59).…”

Section: Biochemical Evidence Of Op Hepatotoxicitysupporting

confidence: 70%

Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

Karami‐Mohajeri

Ahmadipour

Rahimi

et al. 2017

Archives of Industrial Hygiene and Toxicology

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Organophosphorus pesticides (OPs) are widely used volatile pesticides that have harmful effects on the liver in acute and chronic exposures. This review article summarises and discusses a wide collection of studies published over the last 40 years reporting on the effects of OPs on the liver, in an attempt to propose general mechanisms of OP hepatotoxicity and possible treatment. Several key biological processes have been reported as involved in OP-induced hepatotoxicity such as disturbances in the antioxidant defence system, oxidative stress, apoptosis, and mitochondrial and microsomal metabolism. Most studies show that antioxidants can attenuate oxidative stress and the consequent changes in liver function. However, few studies have examined the relationship between OP structures and the severity and mechanism of their action. We hope that future in vitro, in vivo, and clinical trials will answer the remaining questions about the mechanisms of OP hepatotoxicity and its management.

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Section: Biochemical Evidence Of Op Hepatotoxicitysupporting

confidence: 70%

Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

Karami‐Mohajeri

Ahmadipour

Rahimi

et al. 2017

Archives of Industrial Hygiene and Toxicology

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“…Organophosphorus (OP) pesticides are finding increasing use in recent years since they are biodegradable and therefore persist in the environment only for a short time. Because of their low persistence, repeated applications of these pesticides are being practiced for the control of pests in agricultural fields and thereby large quantities find their way into water bodies (Jyothi and Narayan, 1999). A large number of pesticides are commonly used to control various agricultural pests; however, their toxicological impact also extends to nontarget species like fish (Naqvi and Vaishnavi, 1993).…”

Section: Introductionmentioning

confidence: 99%

Histopathological changes in the gill and liver tissues of freshwater fish, Cirrhinus mrigala exposed to dichlorvos

Velmurugan¹,

Selvanayagam²,

Cengiz

et al. 2009

Braz. arch. biol. technol.

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“…80 El-Shenawy et al, 77 reported that exposing mice to diazinon caused degeneration of renal tubules, atrophy of glomeruli and interstitial inflammatory cells infiltrations. Jyothi et al, 81 reported the increase in urea and creatinine in the catfish, Clarias batrachus exposed to sublethal concentration of two pesticides, carbaryl, a carbamate and phorate, an organophosphorus insecticide for 7days. The present results revealed also a significant increase in serum creatinine and urea in response to diazinon toxicity.…”

mentioning

confidence: 99%

Ameliorative Effect of Lycopene and Vitamin E on Some Haematological and Biochemical Parameters of Oreochromis niloticus Against Diazinon Toxicity

Ibrahim¹

2014

APAR

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The present investigation aimed to determine the toxicological effects of diazinon (DZN) pesticide on hematological and biochemical parameters of the widely consumed Oreochromis niloticus. Adult specimens of Oreochromis niloticus were exposed to two sublethal concentrations (0.76 and 2.3mg/l) of DZN against the ameliorative effect of lycopene (10mg/kg) and vitamin E (50mg/kg) for 14 and 28 days. Empirical data of results obtained were subjected to statistical analysis of variance (ANOVA) to test the effects of DZN, lycopene (LYC), vitamin E (VE) and exposure periods. DZN significantly led to decline in red blood cell count (RBC's), blood haemoglobin (Hb), haematocrit value (Hct), white blood cell count (WBC's) and lymphocytes (LYM). While, the mean values of mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), neutrophils (NEU), monocytes (MON), eosinophils (EOS), serum protein (total protein, albumin and globulin), glucose, AST, ALT, ALP, urea and creatinine were significantly increased from the control values. Lycopene and vitamin E supplementation play appositive role in detoxification of DZN toxicity. The results suggest that DZN can negatively affect the hematology and physiology of fish. It was observed that supplementation of lycopene and vitamin E decreases the toxic effect of diazinon. Keywords

show abstract

Certain pesticide-induced carbohydrate metabolic disorders in the serum of freshwater fish Clarias batrachus (Linn.)

Cited by 71 publications

References 14 publications

Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

Histopathological changes in the gill and liver tissues of freshwater fish, Cirrhinus mrigala exposed to dichlorvos

Ameliorative Effect of Lycopene and Vitamin E on Some Haematological and Biochemical Parameters of Oreochromis niloticus Against Diazinon Toxicity

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