Cervical Cancer Screening of Adolescents Should Not Be Encouraged

Henrique, Laílca Quirino; Campaner, Adriana Bittencourt; dʼAvila, Flavia Salomão

doi:10.1097/lgt.0000000000000273

Cited by 6 publications

(4 citation statements)

References 23 publications

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“…The prevalence of cytological abnormalities in our sample was 8.9%, slightly higher than the Israeli rates (4.78%), a study published in 2014 (Bassal et al, 2014) and the data collected at public hospital in Brazil, which was 5% (Henrique et al, 2017). The most prevalent cytological alterations in our total population were: ASC-US with 6.5% of the total (73.19% of the altered cytologies), LSIL with 1.82% (20.50% of the altered cytologies), ASC-H with 0.24% (2.69% of the altered cytologies), HSIL with 0.18% (2.03% of the altered cytologies) and AGC with 0.13% (1.48% of the altered cytologies).…”

Section: Resultscontrasting

confidence: 69%

Evaluation of 1,030,482 Cervical Smear Results in Brazilian Population

Campaner¹,

Fernandes²

2023

Asian Pac J Cancer Prev

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Background:The objective was to determine the prevalence of abnormal cytologic smears in a large population of a Brazilian city. Methods: Retrospective study of cervical cytology results performed at a private laboratory in São Paulo -Brazil. A total of 1,030,482 cytology tests were performed between January 2010 and December 2015. Results: Among the satisfactory cytologies, we observed abnormal results in 8.9% (91,371). Analyzing the proportion of exams with altered results over the years, there was no change in these rates. We observed that the proportion of abnormal exams decreased with increasing age. Atypical squamous cells of undetermined significance, possibly non-neoplastic (ASC-US) cytology was the most common abnormality found in the general population with 73.19%, followed by low-grade intraepithelial lesion (LSIL) with 20.5%; these 2 cytological abnormalities add up to 93.69 % of all abnormal results. There was an increase in ASC-US with advancing age, a decrease in prevalence of LSIL, especially after the age of 30 and high-grade intraepithelial lesion (HSIL) shows two peaks of elevation, respectively in the age groups of 30-39 years and over 70 years. Conclusion: Women under the age of 30 showed a higher prevalence of cytological abnormalities, however most of these changes are low-grade lesions. In older women, cytological abnormalities are largely high-grade lesions, requiring greater care to prevent progression to cancer.

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Section: Resultscontrasting

confidence: 69%

Evaluation of 1,030,482 Cervical Smear Results in Brazilian Population

Campaner¹,

Fernandes²

2023

Asian Pac J Cancer Prev

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“…in a comprehensive study by the Turkish Cervical Cancer and Cervical Cytology research group, the abnormal cytology prevalence rate in women of all ages was 1.8% 9 . Additionally, a 9% to 19% prevalence rate of abnormal cytology in adolescents and young adults has been reported in previous studies 10,11 . These higher rates of cytologic abnormalities as compared with adult population can be explained by the increased hPv infection rate at these ages.…”

Section: Discussionmentioning

confidence: 53%

The Effect of Age on Cervical Cancer Screening in Women Aged 20-29

Tuncer

2020

ACC

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no definite consensus exists currently regarding the appropriate age at which to start cervical cancer screening. we analyzed the effectiveness of age in abnormal histology outcomes in women aged 20-29. data on women aged 20-29 having undergone opportunistic cervical cancer screening with cytology during the 2014-2019 period were retrospectively reviewed. Based on cytology outcomes, human papillomavirus test results (if present), age and clinical decision, patients underwent either colposcopy or observation. The effects of age and other epidemiologic factors on histologic diagnoses of cervical intraepithelial neoplasia (Cin) or cancer [Cin (+)] were analyzed in univariate and binomial logistic regression analyses. Among 1649 women, Cin (+) lesions were observed in 61 (3.7%) women. The occurrence of Cin (+) lesions increased 1.149 times each year; thus, women aged 25-29 were more likely to have Cin (+) than those aged 20-24 (4.4% vs. 2.1%; p=0.019). A significant determinant of Cin (+) was the increase in age, i.e. women aged 20-29. Accordingly, considering age is crucial for the diagnosis of Cin (+) in cancer screening.

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“…A prevalência de lesões de alto grau, em adolescentes, mostrou-se inferior quando comparada à população alvo do screening. 8 Observamos que o percentual de NIC II (60%) encontrado nas avaliações histológicas iniciais era semelhante quando comparado a estudo (70%) que avaliou alterações histológicas em mulheres abaixo de 21 anos (apesar do viés da faixa etária), tendo alta probabilidade de regressão. O percentual de NIC III aqui mostrado (20%) também foi semelhante (16,2%), 10 divergindo apenas quanto a presença de carcinoma.…”

Section: Discussionunclassified

Lesões cervicais de alto grau em adolescentes e fatores clínicos‑epidemiológicos associados

Miranda

Peixoto

2023

Rev. Med. UFC

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Objetivo: Avaliar prevalência de lesões cervicais de alto grau em adolescentes em maternidade terciária, bem como fatores clínico-epidemiológicos correlacionados. Métodos: Estudo retrospectivo caso-controle, que avaliou exames citopatológios, colposcópicos e histopatológicos, sexarca e paridade de adolescentes de 10 a 19 anos, no período de 2016 a 2018. Resultados: Foram coletados 2697 exames citopatológicos no período do estudo, das quais apenas 6 corresponderam a lesão intraepitelial escamosa de alto grau (LIEAG) em adolescentes, compondo o grupo de casos. Não houve casos de carcinoma cervical. O grupo controle com 33 pacientes correspondeu às adolescentes com citopatológico normal. A média da sexarca foi de 14,8 e 14,3 anos nos grupos caso e controle, respectivamente. Não houve diferença estatisticamente significativa quando comparadas sexarca (p = 0,464) e paridade (p>0,999). Conclusão: Apesar do rastreio de câncer de colo de útero para adolescentes não ser preconizado pelo Ministério da Saúde, persiste a prática da coleta entre alguns profissionais. A baixa prevalência (0,22%) de lesões cervicais de alto grau em citopatológico nesse grupo foi reafirmada, podendo ser ainda menor quando avaliados resultados histopatológicos. Não houve casos de câncer de colo. Fatores associados, como sexarca e paridade, não foram estatisticamente significativos.

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Cervical Cancer Screening of Adolescents Should Not Be Encouraged

Abstract: The natural history of HPV infection shows it is transient in young women, with most cases regressing within 2 years of presentation. Our data confirm that screening of adolescents is not recommended because serious cytological abnormalities and cancer are rare in this group.

Cited by 6 publications

References 23 publications

Evaluation of 1,030,482 Cervical Smear Results in Brazilian Population

Evaluation of 1,030,482 Cervical Smear Results in Brazilian Population

The Effect of Age on Cervical Cancer Screening in Women Aged 20-29

Lesões cervicais de alto grau em adolescentes e fatores clínicos‑epidemiológicos associados

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