“…Due to its possible occurrence within three different anatomical compartments, it is characterized by a diversity of symptoms, most of them being being highly unspecific, which significantly elongates delays the time between perforation and final diagnosis followed by institution ofand appropriate targeted management. Despite the markedly improvedmarked improvement in diagnostic methods as well as inand medical care being provided in intensive care units the medical care provided in intensive care units, esophageal perforation remains to beis still associated with a high mortality rate of 5-40%, orand, if the disease is diagnosed with a delay ofthe diagnosis is delayed by more than 24 h, the mortality rate is as high as 50% [1,2,3]. Due to the diversity of potential mechanisms leading to perforation, non-specificity of clinical symptoms, and variety of therapeutic procedures, no uniform guidelines have been established to date with regard to the management of patients with this condition.…”