Cervical spinal cord stimulation in cerebral ischemia

Upadhyaya, Cheerag; Sagher, Oren

doi:10.1007/978-3-211-33079-1_36

Cited by 6 publications

(2 citation statements)

References 50 publications

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“…In conclusion, new perspectives in challenging neurosurgical clinical fields such as cerebral ischemia and vasospasm are called for [62,63] . In particular, the role of a 'functional' revascularization in chronic ischemic stroke in high-risk patients and in the elderly, along with a 'hemodynamic-enhancing-surgery salvage strategy' in severe vasospastic patients harboring SAH, seems promising as a new trend of functional neurosurgery in cerebrovascular diseases.…”

Section: The Futurementioning

confidence: 99%

Spinal Cord Stimulation and Cerebral Hemodynamics: Updated Mechanism and Therapeutic Implications

Visocchi

Pepa

Esposito

et al. 2011

Stereotact Funct Neurosurg

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The effects of spinal cord stimulation (SCS) on cerebral blood flow (CBF) are well known based on experimental investigations, and its vasodilator effect on peripheral arteries is widely used in clinical settings in the treatment of peripheral vascular disease. Since Hosobuchi’s [Appl Neurophysiol 1985;48:372–376] first observations on the effects of SCS on CBF were published 22 years ago, many advances have been made in understanding SCS-mediated effects on CBF. This paper reviews the main laboratory observations and analyzes the most significant neurophysiological theories on the SCS-mediated effect on CBF. Most significant experimental data have been discussed, with specific reference to possible mechanisms such as ‘functional reversible sympathectomy’, cerebral infarction and related ischemic edema, hemodynamic deterioration in experimental combined ischemic-traumatic brain injury and cerebral vasospasm. The authors revised the published experiences in humans with hypoperfusion syndromes and ‘adjuvant’ locoregional CBF increase in chemotherapy of brain tumors. SCS represents a new perspective in challenging neurosurgical clinical fields such as cerebral ischemia and vasospasm, and seems promising as a new trend of functional neurosurgery in cerebrovascular diseases.

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Section: The Futurementioning

confidence: 99%

Spinal Cord Stimulation and Cerebral Hemodynamics: Updated Mechanism and Therapeutic Implications

Visocchi

Pepa

Esposito

et al. 2011

Stereotact Funct Neurosurg

View full text Add to dashboard Cite

show abstract

“…Recently, several studies have reported that high cervical SCS improved pain caused by upper extremity ischemia, brachial plexus injury, so-called failed neck surgery, and CRPS 13,21) . Although the precise mechanism of this effect remains unclear, high-level stimulation might relieve pain by modulation of the dorsal column, the spinothalamic tracts, and the descending inhibi- tory pain pathway 13) , an increase in peripheral blood flow may also affect the alleviation of pain 20) . Cervical spinal cord stimulation has been less studied than thoracic spinal cord stimulation.…”

Section: Discussionmentioning

confidence: 99%

High-Level Cervical Spinal Cord Stimulation Used to Treat Intractable Pain Arising from Transverse Myelitis Caused by Schistosomiasis

Kim

Hong

Lee

2010

J Korean Neurosurg Soc

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J Korean Neurosurg Soc 47 : [151][152][153][154] 2010 The efficacy of spinal cord stimulation (SCS) for treatment of various chronic painful conditions is well established. Very few reports have documented the use of SCS for treatment of chronic pain after spinal cord injury. We present a case showing a good outcome after such treatment, and suggest that high cervical stimulation may be efficacious. A 53-year-old male underwent SCS on the C1-3 level for treatment of intractable neuropathic pain below the T3 level, and in the upper extremities, arising from spinal cord injury resulting from transverse myelitis caused by schistosomiasis. High cervical SCS significantly improved the pain in the upper extremities and at the T3-T10 dermatome level. The patient continues to report excellent pain relief 9 months later. The present case suggests that high cervical stimulation may improve chronic pain in the upper extremities and the T3-T10 dermatome level arising from spinal cord injury.

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Effects of electrical cervical spinal cord stimulation on cerebral blood perfusion, cerebrospinal fluid catecholamine levels, and oxidative stress in comatose patients

Liu

Tan

Liao

Acta Neurochirurgica Supplementum

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Cervical spinal cord stimulation in cerebral ischemia

Cited by 6 publications

References 50 publications

Spinal Cord Stimulation and Cerebral Hemodynamics: Updated Mechanism and Therapeutic Implications

Spinal Cord Stimulation and Cerebral Hemodynamics: Updated Mechanism and Therapeutic Implications

High-Level Cervical Spinal Cord Stimulation Used to Treat Intractable Pain Arising from Transverse Myelitis Caused by Schistosomiasis

Effects of electrical cervical spinal cord stimulation on cerebral blood perfusion, cerebrospinal fluid catecholamine levels, and oxidative stress in comatose patients

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