Cervical Vagus Nerve Neurilemmoma Mimicking Parathyroid Adenoma

Calero, Antonio Prat; Cascales‐Sanchez, P.; Moreno, Agustina Martínez; Corellano, J. Valer

doi:10.1016/j.otoeng.2017.02.008

Cited by 1 publication

(2 citation statements)

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“…At this location, a 1.5 cm tumor was identified during surgery and histology showed a schwannoma of the vagus nerve. Although the authors describedthe schwannoma as behaving like a mimicker of a parathyroid adenoma, we could not find clear evidence of 99m Tc-sestamibi uptake by the schwanoma (as opposed to by a parathyroid adenoma responsible for the patient’s persistent hyperparathyroidism), because no SPECT/CT scan was done and no 99m Tc-sestamibi scan images were shown in the article ( 20 ).…”

Section: Discussionmentioning

confidence: 77%

“…We searched the literature for previous cases of 99m Tc-sestamibi uptake by a cervical schwanoma. The only potentially relevant article reported the case of a 53-year-old patient with primary hyperparathyroidism, who, after multiple negative localization tests ( 99m Tc-sestamibi scan, cervical ultrasound and cervical MRI), had removal of both left parathyroid glands ( 20 ). Three years later, because of persistent hyperparathyroidism, a new 99m Tc-sestamibi scan was performed showing uptake in the right cervical region, followed by a cervical CT scan that revealed a 1.1 cm nodule between the jugular vein and the right carotid.…”

Section: Discussionmentioning

confidence: 99%

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Esophageal schwannoma mimicking non-functional parathyroid adenoma on 99mTc-sestamibi imaging: a case report

Fiore,

Gombert,

La Rosa

et al. 2024

Front. Endocrinol.

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Technetium-99m sestamibi single-photon emission computed tomography/computed tomography (99mTc-sestamibi SPECT/CT) is a mainstay of the pre-operative localization of parathyroid lesions. We report here the case of a 30 year-old woman with a fortuitously discovered 2 cm cervical mass for which a parathyroid origin was originally suspected due to its retro-thyroidal localization and a personal history of nephrolithiasis. Normal serum calcium and parathyroid hormone (PTH) levels excluded primary hyperparathyroidism, raising suspicion of a non-functional parathyroid adenoma, and SPECT/CT imaging showed that the mass was 99mTc-sestamibi-avid. Fine-needle aspiration (FNA) was performed; cytology was non-diagnostic but the needle washout was negative for thyroglobulin, calcitonin and PTH, arguing against a thyroidal or parathyroidal origin of the mass. Core needle biopsy revealed a schwannoma, ostensibly originating from the recurrent laryngeal nerve; upon surgical resection, it was finally found to arise from the esophageal submucosa. This case illustrates the fact that endocrinologists, radiologists, nuclear medicine, head and neck, and other specialists investigating patients with cervical masses should be aware that schwannomas need to be considered in the differential diagnosis of focal 99mTc-sestamibi uptake in the neck region.

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Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%