T he global prevalence of obesity (body mass index [BMI], 30 kg/m 2 ) has tripled since 1975, and it is estimated that, in 2016, >1.9 billion adults were overweight (BMI, 25e29.9 kg/m 2 ), of which >650 million adults were obese. 1 Among women giving birth in the United States in 2014, 50.4% were either overweight or obese. 2 In addition, adults with a BMI of kg/m 2 comprise the most rapidly growing class of obesity in the United States. 3 Pregnant women who are classified as overweight or obese are known to be at increased risk for adverse maternal and fetal/neonatal outcomes. 4,5 However, the increased risk of pregnancy complications with each obesity class over that for women with standard BMI has not been assessed systematically. Given the high prevalence of obesity among women of childbearing age, the importance of estimating pregnancy risk with increasing BMI categories has become more pertinent than ever.
ObjectiveThe objective of this study was to metaanalyze data that compares pregnancy outcomes in women with obesity and that are stratified by obesity class, with the view to counselling women and informing preventative strategies preconceptionally and during pregnancy.
MethodsThis study was conducted as part of study to scrutinize the effect of obesity on mode of delivery; the study protocol