Cesarean Section in a Pregnant Woman with COVID-19: First Case in Portugal

Lyra, Joana; Valente, Rita; Rosário, Marta; Guimarães, Mariana

doi:10.20344/amp.13883

Cited by 50 publications

(60 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of the 30 case reports, 29 reports described neonatal outcomes of women in their third trimester, whereas only 2 case reports described outcomes of women in their second trimester. 13 , 18 , 25 , 27 , 28 , 29 , 30 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 66 To date, no reports are available describing the assessment for the presence of SARS-CoV-2 in products of conception of a first-trimester pregnancy. Most women in case report studies (32/44) underwent CD with a resultant CD rate of 73%.…”

Section: Resultsmentioning

confidence: 99%

Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis

Kotlyar

Grechukhina

Chen

et al. 2021

American Journal of Obstetrics and Gynecology

562

525

View full text Add to dashboard Cite

Objective This study aimed to conduct a systematic review of the current literature to determine estimates of vertical transmission of coronavirus disease 2019 based on early RNA detection of severe acute respiratory syndrome coronavirus 2 after birth from various neonatal or fetal sources and neonatal serology. Data Sources Eligible studies published until May 28, 2020, were retrieved from PubMed, EMBASE, medRxiv, and bioRxiv collection databases. Study Eligibility Criteria This systematic review included cohort studies, case series, and case reports of pregnant women who received a coronavirus disease 2019 diagnosis using severe acute respiratory syndrome coronavirus 2 viral RNA test and had reported data regarding the testing of neonates or fetuses for severe acute respiratory syndrome coronavirus 2 immediately after birth and within 48 hours of birth. A total of 30 eligible case reports describing 43 tested neonates and 38 cohort or case series studies describing 936 tested neonates were included. Study Appraisal and Synthesis Methods The methodological quality of all included studies was evaluated by a modified version of the Newcastle-Ottawa scale. Quantitative synthesis was performed on cohort or case series studies according to the neonatal biological specimen site to reach pooled proportions of vertical transmission. Results Our quantitative synthesis revealed that of 936 neonates from mothers with coronavirus disease 2019, 27 neonates had a positive result for severe acute respiratory syndrome coronavirus 2 viral RNA test using nasopharyngeal swab, indicating a pooled proportion of 3.2% (95% confidence interval, 2.2–4.3) for vertical transmission. Of note, the pooled proportion of severe acute respiratory syndrome coronavirus 2 positivity in neonates by nasopharyngeal swab in studies from China was 2.0% (8/397), which was similar to the pooled proportion of 2.7% (14/517) in studies from outside of China. Severe acute respiratory syndrome coronavirus 2 viral RNA testing in neonatal cord blood was positive in 2.9% of samples (1/34), 7.7% of placenta samples (2/26), 0% of amniotic fluid (0/51), 0% of urine samples (0/17), and 9.7% of fecal or rectal swabs (3/31). Neonatal serology was positive in 3 of 82 samples (3.7%) (based on the presence of immunoglobulin M). Conclusion Vertical transmission of severe acute respiratory syndrome coronavirus 2 is possible and seems to occur in a minority of cases of maternal coronavirus disease 2019 infection in the third trimester. The rates of infection are similar to those of other pathogens that cause congenital infections. However, given the paucity of early trimester data, no assessment can yet be made regarding the rates of vertical transmission in early pregnancy and potential risk for consequent fetal morbidity and mortality.

show abstract

Section: Resultsmentioning

confidence: 99%

Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis

Kotlyar

Grechukhina

Chen

et al. 2021

American Journal of Obstetrics and Gynecology

562

525

View full text Add to dashboard Cite

show abstract

“… 90 Iran 4/17/20 1 1 1 1 4 NR Fever Recovered in 1 wk Critical 0 Formula Yes NR DOL7 Alzamora et al 42 Peru 4/18/20 1 1 1 1 2 Tested and neg Mild respiratory distress, cough Recovered, time NR Severe 0 Formula Yes NR DOL6 Lyra et al. 91 Portugal 4/20/20 1 1 0 0 3 NR Mild 0 Formula Yes NR DOL7 Yan et al. 29 China 4/23/20 86 85 20 0 1 NR Mild to critical 0 NR NR NR NR* Kelly et al.…”

Section: Introductionmentioning

confidence: 99%

A review of newborn outcomes during the COVID-19 pandemic

Kyle

Glassman

Khan

et al. 2020

Seminars in Perinatology

View full text Add to dashboard Cite

As the COVID-19 pandemic continues to spread worldwide, it is crucial that we determine populations that are at-risk and develop appropriate clinical care policies to protect them. While several respiratory illnesses are known to seriously impact pregnant women and newborns, preliminary data on the novel SARS-CoV-2 Coronavirus suggest that these groups are no more at-risk than the general population. Here, we review the available literature on newborns born to infected mothers and show that newborns of mothers with positive/suspected SARS-CoV-2 infection rarely acquire the disease or show adverse clinical outcomes. With this evidence in mind, it appears that strict postnatal care policies, including separating mothers and newborns, discouraging breastfeeding, and performing early bathing, may be more likely to adversely impact newborns than they are to reduce the low risk of maternal transmission of SARS-CoV-2 or the even lower risk of severe COVID-19 disease in otherwise healthy newborns.

show abstract

“…La Tabla 3 , resume la información clínica básica en los 16 reportes de casos, en los que se destacan 3 casos de probable transmisión vertical, en particular el trabajo de Vivanti y cols de Francia que demuestra la presencia de SARS-CoV-2 en liquido amniótico al momento de la cesárea, en la placenta y en la sangre neonatal. [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47] El detalle de todos los casos de probable transmisión al recién nacido, esta descrito en Tabla 4.…”

Section: Resultsunclassified

Embarazo y nuevo coronavirus: Experiencia global reportada

M²,

et al. 2020

Rev. chil. obstet. ginecol.

View full text Add to dashboard Cite

Salud ha reportado recientemente que el nuevo foco de la pandemia global de la enfermedad Covid-19 es el continente americano. Objetivo: Realizar una revisión de la literatura sobre la experiencia internacional de la pandemia Covid 19 y embarazo. Método: Se realiza una búsqueda de la base de datos PubMed para las palabras clave Pregnancy / Pregnant / Novel Coronavirus / SARS-CoV-2 / Covid-19, desde el 1 de noviembre 2019 hasta el 21 de mayo 2020. Resultados: Un total de 365 artículos fueron inicialmente seleccionados de acuerdo con la estrategia de búsqueda diseñada. El total de artículos revisados de acuerdo con los criterios fueron 42. Las series clínicas seleccionadas acumularon un total de 1098 embarazadas y enfermedad de Covid-19. Las co-morbilidades mas frecuentes fueron hipertensión arterial, diabetes mellitus, obesidad y asma. La mortalidad en relación con el total de pacientes fue de un 1,2 % y la transmisión al recién nacido de 1,7% (15 de 875). Conclusión: La información obtenida permite inferir que la presentación clínica de la enfermedad es a lo menos equivalente a la de mujeres de la misma edad no embarazadas. Dada la severidad de la enfermedad por SARS-CoV-2 reportada, las lecciones aprendidas deben ser rápidamente asimiladas y utilizadas en el contexto de la situación nacional epidémica.

show abstract

Cesarean Section in a Pregnant Woman with COVID-19: First Case in Portugal

Cited by 50 publications

References 1 publication

Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis

Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis

A review of newborn outcomes during the COVID-19 pandemic

Embarazo y nuevo coronavirus: Experiencia global reportada

Contact Info

Product

Resources

About