2023
DOI: 10.3390/bioengineering10030309
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CFD Computation of Flow Fractional Reserve (FFR) in Coronary Artery Trees Using a Novel Physiologically Based Algorithm (PBA) Under 3D Steady and Pulsatile Flow Conditions

Abstract: A novel physiologically based algorithm (PBA) for the computation of fractional flow reserve (FFR) in coronary artery trees (CATs) using computational fluid dynamics (CFD) is proposed and developed. The PBA was based on an extension of Murray’s law and additional inlet conditions prescribed iteratively and was implemented in OpenFOAM v1912 for testing and validation. 3D models of CATs were created using CT scans and computational meshes, and the results were compared to invasive coronary angiographic (ICA) dat… Show more

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Cited by 3 publications
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“…The presented framework can be used to integrate data obtained by computerized fractional flow reserve (cFFR). Traditionally, in cFFR, the complex geometry of the coronary tree and the Navier–Stokes equations are used to compute the fluid dynamics [ 31 ]. The resulting fluxes computed via cFFR can be used as input in our hybrid model.…”
Section: Discussion Conclusion and Future Workmentioning
confidence: 99%
“…The presented framework can be used to integrate data obtained by computerized fractional flow reserve (cFFR). Traditionally, in cFFR, the complex geometry of the coronary tree and the Navier–Stokes equations are used to compute the fluid dynamics [ 31 ]. The resulting fluxes computed via cFFR can be used as input in our hybrid model.…”
Section: Discussion Conclusion and Future Workmentioning
confidence: 99%