A hybrid transition trip-dot sizing and placement test technique was developed in support of recent experimental research on a hybrid wing-body configuration under study for the NASA Environmentally Responsible Aviation project. The approach combines traditional methods with Computational Fluid Dynamics. The application had threedimensional boundary layers that were simulated with either fully turbulent or transitional flow models using established Reynolds-Averaged Navier-Stokes methods. Trip strip effectiveness was verified experimentally using infrared thermography during a low-speed wind tunnel test. Although the work was performed on one specific configuration, the process was based on fundamental flow physics and could be applicable to other configurations. Nomenclature Av data average over an interval s distance along a surface b 1b 3 spanwise coordinate for leading-edge sweep break U ∞ free-stream reference velocity C f skin friction coefficient x, y, z body-axis Cartesian coordinates C p pressure coefficient u, v, w Cartesian velocity components c wing chord c ref reference chord angle of attack, deg. H 12 boundary-layer shape factor, boundary layer thickness k roughness height boundary layer displacement thickness M Mach number boundary layer momentum thickness Ra data range (maximum-minimum) over an interval leading-edge sweep angle, deg. Re cref reference chord Reynolds number, U ∞ c ref / viscosity Re k roughness height Reynolds number, u k k / k kinematic viscosity, Re x length Reynolds number, U ∞ x / density Re momentum thickness Reynolds number, U e / Subscripts e value at edge of boundary layer ∞ free-stream reference conditions k value at roughness height