CGF with Bio-Oss Collagen as Grafting Materials for Immediate Implants after Osteotome Sinus Floor Elevation, a Retrospective Study

Abstract

Background: Osteotome sinus floor elevation (OSFE) procedure with immediate implant placement proved to be efficient procedure in the atrophic maxilla, where bone regeneration is required the most. The purpose of this retrospective study was to radiologically evaluate collagen with Concentrated Growth Factor (CGF) as grafting materials for OSFE with simultaneously implant placement in the atrophic maxilla after one year of being functional loaded. Methods: 126 implants were inserted for 123 patients. Patients included in our criteria with Residual Bone Height (RBH) ≤ 5 underwent OSFE procedure and immediate implant placement with different grafting materials. Group A with no grafting materials, Group B with Bio-Oss bone graft, and Group C with Bio-Oss collagen and CGF. Radiographic measurements assessed at 4 time points follow up after surgery were secondary outcome variables, in addition to Implant Stability Quotient (ISQ) and Bone density (B). Indicators of bone formation were compared at different time points. Appropriate statistics were computed, and statistical significance was indicated by P value 0.05 for all tests. Results: Total Implants Survival Rate (ISR). was 96%. There was a significant positive relationship between RBH and ISR, [r (126) = .359, p = .000]. Higher indicators for endo-sinus bone gain were recorded in both grafted groups. Total Bone Resorption (TBR1) and (TBR2)were significantly decreased in both grafted groups compared to non-grafted group (P = .004, P = .000). (Graft size) D was a positive predictor for ISR at three time points. D0, (odds ratio [OR] 8.06; 95% CI 1.59 to 38.24; P = .010). D1, (OR 96.58; 95% CI 1.69 to 5.52; P = .027). D2, (OR 4.97; 95% CI 1.29 to 19.19; P = .020) Conclusion: The combination of collagen with CGF as grafting material is a reliable protocol after OSFE with simultaneously implant placement in the atrophic maxilla.