CH-19 Sweet, a Non-Pungent Cultivar of Red Pepper, Increased Body Temperature and Oxygen Consumption in Humans

Effects of CH-19 Sweet, a Non-Pungent Cultivar of Red Pepper, in Decreasing the Body Weight and Suppressing Body Fat Accumulation by Sympathetic Nerve Activation in Humans

“…It has been suggested that CH-19 Sweet and capsiate, an effective ingredient of CH-19 Sweet, were useful for the suppression of body fat accumulation because they were not pungent, unlike capsaicin, but had the same physiological effects. [9][10][11][12]32) Indeed, in the present study, we found that the repeated intake of CH-19 Sweet for two weeks reduced body weight and suppressed body fat accumulation in humans. The anti-obese effects of CH-19 Sweet or capsiate should be confirmed by a largescale future experiment.…”

“…in mice 9) as well as by a single CH-19 Sweet administration (0.1 g/kg wt.) in humans, 12) so we speculated that the total energy expenditure would increase by repeated intake of CH-19 Sweet for two weeks in humans. We estimated that the total metabolic rate would increase by an average of at least 10% per day throughout the treatment period, although this speculation was not based on any experimental data.…”

Capsiate, a Nonpungent Capsaicin Analog, Increases Endurance Swimming Capacity of Mice by Stimulation of Vanilloid Receptors

“…These results imply that we can ingest a large amount of nonpungent capsiate and CH-19 Sweet, making its application very probable. CH-19 Sweet ingestion has elevated oxygen consumption and body temperature in humans, 29) and these effects may have been induced by the capsiate present in CH-19 Sweet.…”

Capsiate administration results in an uncoupling protein-3 downregulation, an enhanced muscle oxidative capacity and a decreased abdominal fat content in vivo

“…Infrared thermography and indirect calorimetry experiments have shown that a single intake of 'CH-19 sweet' fruit increases body temperature and basal oxygen consumption in resting humans, hence suggesting that CH-19 sweet promotes thermogenesis and energy consumption. 6 The aim of this study was to determine whether chronic administration of capsiate affects whole-body fat composition and skeletal muscle energy metabolism at rest and during exercise. We used an original experimental setup allowing muscle function to be assessed strictly noninvasively in situ using magnetic resonance (MR) techniques and mechanical performance measurements.…”