2024
DOI: 10.1038/s41598-024-61125-z
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Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism

Donghyeon Yeo,
Yeo Gyun Yun,
Seong-Jin Shin
et al.

Abstract: Oral cancer stands as a prevalent maligancy worldwide; however, its therapeutic potential is limited by undesired effects and complications. As a medicinal edible fungus, Chaga mushroom (Inonotus obliquus) exhibits anticancer effects across diverse cancers. Yet, the precise mechanisms underlying its efficacy remain unclear. We explored the detailed mechanisms underlying the anticancer action of Chaga mushroom extract in oral cancer cells (HSC-4). Following treatment with Chaga mushroom extracts, we analyzed ce… Show more

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