Chain Entanglements and Hydrogen Bonds in Carbopol Microgel Reinforced Hydrogel

Zhang, Xiu Yin; Zhao, Chuanzhuang; Xiang, Nanping; Li, Wei

doi:10.1002/macp.201600245

Cited by 22 publications

(16 citation statements)

References 33 publications

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“…49,50 An alternative mechanism to obtain stiffer gels during or after deformation are gels that change their composition or architecture when the sample is strained. [51][52][53] In contrast to the aforementioned mechanism, this type of strain-stiffening is slower and far from reversible. The PIC gels are intrinsically strain-stiffening, but when crosslinked with self-assembled virus-capsids, we also find the second mechanism in our material.…”

Section: Resultsmentioning

confidence: 99%

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: approaches towards capsid rupture and gel repair

Schoenmakers¹,

Schoonen

Rutten³

et al. 2018

Soft Matter

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Biological hydrogels can become many times stiffer under deformation. This unique ability has only recently been realised in fully synthetic gels. Typically, these networks are composed of semi-flexible polymers and bundles and show such large mechanical responses at very small strains, which makes them particularly suitable for application as strain-responsive materials. In this work, we introduced strain-responsiveness by crosslinking the architecture with a multi-functional virus-like particle. At high stresses, we find that the virus particles disintegrate, which creates an (irreversible) mechanical energy dissipation pathway, analogous to the high stress response of fibrin networks. A cooling-heating cycle allows for re-crosslinking at the damaged site, which gives rise to much stronger hydrogels. Virus particles and capsids are promising drug delivery vehicles and our approach offers an effective strategy to trigger the release mechanically without compromising the mechanical integrity of the host material.

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Section: Resultsmentioning

confidence: 99%

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: approaches towards capsid rupture and gel repair

Schoenmakers¹,

Schoonen

Rutten³

et al. 2018

Soft Matter

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“…Optical scattering was controlled by adding TiO 2 particles to the water phase at 0.01–0.1% w/w. Carbomer 940 (C1477, Spectrum, New Brunswick, NJ) was used to enhance mechanical strength of TMM formulations intended as solid imaging targets, thus allowing the use of injection molding techniques [54] . Carbomer was dissolved in DI water and added to the TMM after emulsification from 0.05% to 0.3% w/w.…”

Section: Methodsmentioning

confidence: 99%

Photoacoustic imaging phantoms for assessment of object detectability and boundary buildup artifacts

et al. 2022

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“…The extract was incorporated until it was integrated into the gel. Lastly, triethanolamine was added, incorporating three drops, to neutralize and reach the desired viscosity and as a pH balancer (Zhang et al, 2016;Singh et al, 2016). The viscosity of the hydrogel was evaluated by emulsion flow curves using a rotational test with a Reolab QC rheometer as a function of the shear rate (0.02 to 100 s-1), using cylindrical concentric geometry CC-27 at a temperature of 27 °C (Bociaga et al, 2019).…”

Section: Methodsmentioning

confidence: 99%

Antimicrobial and Antibiofilm Effect of Hydrogel with Origanum vulgare on Culture of Streptococcus mutans and Streptococcus sobrinus

Vaca-Chávez

Rodríguez‐Rojas

Castillo-Velázquez

et al. 2021

Int. J. Odontostomat.

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The oral cavity is an ecosystem that provides ideal conditions for the growth of bacteria, the Streptococcus genus is important for the formation of biofilms that lead to the development of dental caries, which affects the population worldwide. The world health organization encourages the use of plants thanks to its various therapeutic actions. Origanum vulgare L. (oregano), is an aromatic plant with medicinal and culinary properties. The objective of this study was to investigate the in vitro antimicrobial and antibiofilm activity of the ethanolic extract of oregano, against the growth of Streptococcus mutans and Streptococcus sobrinus ATCC. Leaves of the plant were obtained and the ethanolic extract was made by maceration. Antimicrobial activity was evaluated using the Kirby-Bauer method and compared with 2% chlorhexidine, subsequently the extract was incorporated into a hydrogel and its effect on biofilm formation was assessed by fluorescence microscopy and the main compounds were identified. present in the extratco. The study revealed that the extract presented antimicrobial effect against both strains and at 2% it showed high antimicrobial action compared to chlorhexidine at the same concentration, with average inhibition halos of 26.3 mm and 19 mm for each microorganism analyzed, (p < 0.05). Likewise, the hydrogel prepared with 2% extract significantly eliminated the preformed Streptococcus biofilm, at 24 hours of exposure, due to the presence of a variety of chemical groups, such as sterols, triterpenes, flavonoids, flavanones, flavanonols, lactones. sesquiterpenic, tannins and coumarins. The oregano extract presented high antimicrobial action for both species, with a greater effect towards Streptococcus mutans and an interesting antibiofilm action; These results show the importance of exploring treatment alternatives of plant origin, to be considered as interesting complementary aids in dental therapy.

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Chain Entanglements and Hydrogen Bonds in Carbopol Microgel Reinforced Hydrogel

Cited by 22 publications

References 33 publications

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: approaches towards capsid rupture and gel repair

Virus-like particles as crosslinkers in fibrous biomimetic hydrogels: approaches towards capsid rupture and gel repair

Photoacoustic imaging phantoms for assessment of object detectability and boundary buildup artifacts

Antimicrobial and Antibiofilm Effect of Hydrogel with Origanum vulgare on Culture of Streptococcus mutans and Streptococcus sobrinus

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