2005
DOI: 10.1017/s1047951105001137
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Challenges facing the child, adolescent, and young adult after the arterial switch operation

Abstract: The arterial switch operation is now recognized as the procedure of choice for treatment of infants and children born with the combination of concordant atrioventricular and discordant ventriculo-arterial connections, usually known simply as transposition. Although the Mustard and Senning atrial switch procedures achieved widespread acceptance and success, the accumulating observations at mid- to late follow-up of, first, the increasing frequency of arrhythmias and sudden death, second, late right ventricular … Show more

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Cited by 17 publications
(11 citation statements)
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“…1 These lesions are usually symptom free and several examinations have been made for the assessment of these patients at high risk for myocardial ischaemia. 2 Selective coronary angiography is the current gold standard for detecting anatomic coronary stenosis. [3][4][5] However, it is an invasive, radiant examination and does not provide functional information about myocardial perfusion in the regions irrigated by the stenotic coronary artery.…”
Section: T He Main Cause Of Long-term Morbidity Andmentioning
confidence: 99%
“…1 These lesions are usually symptom free and several examinations have been made for the assessment of these patients at high risk for myocardial ischaemia. 2 Selective coronary angiography is the current gold standard for detecting anatomic coronary stenosis. [3][4][5] However, it is an invasive, radiant examination and does not provide functional information about myocardial perfusion in the regions irrigated by the stenotic coronary artery.…”
Section: T He Main Cause Of Long-term Morbidity Andmentioning
confidence: 99%
“…For example, infants with TGA are typically repaired within the first week of life (Mussatto & Wernovsky, 2005) whereas infants with tetralogy of Fallot may not be repaired until they are between 3 and 6 months of age (Karl, 2008). Infants with TGA were chosen as the focus of this study because it is one of the most common defects and timing of corrective surgery is fairly uniform (Mussatto & Wernovsky, 2005). Additionally, limiting the study to one defect reduced the confounding effects of the unique functional and physiologic characteristics of different types of defects.…”
Section: Trajectories Of Parasympathetic Nervous System Function Befomentioning
confidence: 99%
“…The most common complication of the arterial switch is supravalvular pulmonary stenosis (at the anastomotic site), which is usually seen within the 1st year after surgery but is only severe enough to necessitate balloon angioplasty or open surgical repair with a patch in a small percentage of those patients. LVOT obstruction is rare (51,65). A common finding after a Jatene procedure is dilatation of the neoaortic root (often 3 standard deviations beyond the mean) (66).…”
Section: Dextro-tgamentioning
confidence: 99%
“…While this has been seen in 50% of patients 10 years after surgery, the importance of this finding is unknown. Despite this dilatation, hemodynamically significant neoaortic valve regurgitation is uncommon (65)(66)(67). Dilatation of the aorta is well demonstrated on MR images and can be visible on radiographs (68).…”
Section: Dextro-tgamentioning
confidence: 99%