Waste management represents a challenge due to the rapid increase in waste production and the emergence of new waste types. Overcoming the issue involves using innovative technologies such as nanotechnology. Nanotechnology uses nanomaterials, which are materials that have at least one dimension less than 100 nm. Due to their small size, these materials increase reactivity in processes such as adsorption and oxidation/reduction. The application of nanotechnologies is significant in the production of new materials to replace current raw materials, and in providing novel solutions for waste recycling and disposal. Furthermore, nanofiltration is effective in the treatment of metals, toxic waste, and nonbiodegradable materials of leachate. Nanomaterials, however, represent a safety risk for the environment, and a serious threat to human health due to their small size and long suspension time. This chapter deals with the use of nanotechnology in waste management, including reduction, recycling, treatment, and disposal phases.