Challenges in routine clinical chemistry testing analysis of small molecules

Sepulveda, Jorge L.

doi:10.1016/b978-0-12-813776-5.00009-1

Cited by 12 publications

(5 citation statements)

References 108 publications

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“…Cr, urea, and uric acid contents are applied as serum biochemical markers of kidney injuries; accordingly elevated levels of these factors may reveal kidney deficiencies [ 31 ]. Creatinine is a non-protein nitrogenous agent that is composed of phosphocreatine and creatine in the process of muscle metabolism and some of it is secreted through glomerular filtration [ 32 ]. In similarity to urea, it seems that the Cr secretion could also be influenced by glomerular filtration rate (GFR), suggesting that any modification that diminishes GFR leads to an increase in serum creatinine [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response

Nouri

Izak-Shirian

Fanaei

et al. 2021

Heliyon

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Section: Discussionmentioning

confidence: 99%

Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response

Nouri

Izak-Shirian

Fanaei

et al. 2021

Heliyon

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“…In contrast, increased saliva cortisol concentrations not only influence the overall shape but also have an impact on specific features, in particular on the area around the eyes. Physiologically, circadian secretion rates of cortisol in relation to other hormones or life-style factors can dramatically influence the water exchange between cells and the extracellular space by ion movements along the cell membranes35. Also, cortisol administration in healthy men leads to an expansion of extracellular plasma volume36.…”

Section: Discussionmentioning

confidence: 99%

Patterns of correlation of facial shape with physiological measurements are more integrated than patterns of correlation with ratings

Windhager

Bookstein

Millesi

et al. 2017

Sci Rep

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This article exploits a method recently incorporated in the geometric morphometric toolkit that complements previous approaches to quantifying the facial features associated with specific body characteristics and trait attribution during social perception. The new method differentiates more globally encoded from more locally encoded information by a summary scaling dimension that is estimated by fitting a line to the plot of log bending energy against log variance explained, partial warp by partial warp, for some sample of varying shapes. In the present context these variances come from the regressions of shape on some exogenous cause or effect of form. We work an example involving data from male faces. Here the regression slopes are steepest, and the sums of explained variances over the uniform component, partial warp 1 and partial warp 2 are greatest, for the conventional body mass index, followed by cortisol and, lastly, perceived health. This suggests that physiological characteristics may be represented at larger scale (global patterns), whereas cues in perception are of smaller scale (local patterns). Such a polarity within psychomorphospace, the global versus the focal, now has a metric by which patterns of morphology can be modeled in both biological and psychological studies.

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“…WHO-ISH Cardiovascular disease (CVD) risk prediction charts, were used for arriving at �30% ten-year cardiovascular risk estimates for adults aged 40-69 years [27] (Table 2). Mean salt intake of the population was estimated by applying the Intersalt equation [7,21,[28][29][30] and it was multiplied by 2.54 to arrive at values in grams/day from the estimated sodium, potassium and Creatinine excretion.…”

Section: Definitions Usedmentioning

confidence: 99%

National noncommunicable disease monitoring survey (NNMS) in India: Estimating risk factor prevalence in adult population

et al. 2021

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Background The primary objective of National NCD monitoring survey (NNMS) was to generate national-level estimates of key NCD indicators identified in the national NCD monitoring framework. This paper describes survey study protocol and prevalence of risk factors among adults (18–69 years). Materials and methods NNMS was a national level cross-sectional survey conducted during 2017–18. The estimated sample size was 12,000 households from 600 primary sampling units. One adult (18–69 years) per household was selected using the World Health Organization-KISH grid. The study tools were adapted from WHO-STEPwise approach to NCD risk factor surveillance, IDSP-NCD risk factor survey and WHO-Global adult tobacco survey. Total of 8/10 indicators of adult NCD risk factors according to national NCD disease monitoring framework was studied. This survey for the first time estimated dietary intake of salt intake of population at a national level from spot urine samples. Results Total of 11139 households and 10659 adults completed the survey. Prevalence of tobacco and alcohol use was 32.8% (95% CI: 30.8–35.0) and 15.9% (95% CI: 14.2–17.7) respectively. More than one-third adults were physically inactive [41.3% (95% CI: 39.4–43.3)], majority [98.4% (95% CI: 97.8–98.8)] consumed less than 5 servings of fruits and / or vegetables per day and mean salt intake was 8 g/day (95% CI: 7.8–8.2). Proportion with raised blood pressure and raised blood glucose were 28.5% (95% CI: 27.0–30.1) and 9.3% (95% CI: 8.3–10.5) respectively. 12.8% (95% CI: 11.2–14.5) of adults (40–69 years) had ten-year CVD risk of ≥30% or with existing CVD. Conclusion NNMS was the first comprehensive national survey providing relevant data to assess India’s progress towards targets in National NCD monitoring framework and NCD Action Plan. Established methodology and findings from survey would contribute to plan future state-based surveys and also frame policies for prevention and control of NCDs.

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Challenges in routine clinical chemistry testing analysis of small molecules

Cited by 12 publications

References 108 publications

Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response

Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response

Patterns of correlation of facial shape with physiological measurements are more integrated than patterns of correlation with ratings

National noncommunicable disease monitoring survey (NNMS) in India: Estimating risk factor prevalence in adult population

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