Cremation was a common behavior during the Early period in the Middle Cauca region of Colombia. Nevertheless, few bioarchaeological analyses have focused on understanding this phenomenon. Four funerary urns from the archaeological site Matecaña (Pereira, Risaralda, Colombia) were analyzed to understand the cremation mortuary practice during the Early period (1000 bc–600 ad). For this, the cremains went through an anatomical classification that led to establishing the minimal number of individuals with the landmark system, as well as reconstructing their biological profile and interpreting the macroscopic changes made by heat exposure, such as colorimetry, the degree of cremation, the presence of heat‐induced changes, and the temperature that the incineration reached. The results indicated that the funerary cycle had three processes divided into 11 steps. During the first process, an individual's biological death led to rituals and a temporary deposition. After the skeletonization of the corpse, the second process was the cremation itself. The combustion of at least 28 individuals of different ages (fetuses, infants, and adults) was intense (400°C to over 600°C) and finalized in the third process with their burial in funerary urns. This funerary behavior reflects the long‐term relationship between the living and the dead.