“…This is particularly important especially in the area of core IDSR activities like case definition, case detection, case registration, case reporting and data management. Moreover, only a few studies have been conducted on the evaluation of IDSR core functions in Nigeria (Edo, Kaduna, Anambra, Ekiti, and Osun) but none has been carried out in Oyo State especially with regards to the HCWs' knowledge of IDSR strategy for EPDs [ 17 - 20 ]. However, parts of Oyo State that share international borders with the Republic of Benin such as Iwajowa, Itesiwaju, Atisbo and Saki-west local government are at risk of trans-border transmission of epidemic prone diseases.…”