Over the last decades, Unmanned Aerial Systems (UASs) have gained much attention due to their various applications in different sections. However, their communication range is limited to utilized communication equipment. Therefore, utilization of GSM channels opens a new prospect towards long distance UAV missions and mobile command and control centers. This paper demonstrates new design and development of a small-scale UAV and a Ground Control Station (GCS) using GSM bidirectional communications for Non-Line of Sight (NLoS) long range control. GCSs are considered the front end node in UAV guidance process. Therefore, the proposed GCS employs a two-layer framework to consider all ground pilot requirements. Moreover, a new exploitation of global weather forecast data is added to the GCS. On the other hand, the proposed airborne system utilizes a new integration of different Commercial off-the-Shelf (COTS) components and excludes short range receivers. The ground and flight tests show that stable bidirectional GSM communication is established, reliable hardware integration is accomplished, real time performance is achieved, GCS functional fidelity is obtained, and low cost is maintained. Finally, some qualitative aspects of the proposed platform are presented to address the detailed features.Recently, Unmanned Aerial Vehicles (UAVs) have a great potential in Research and Development (R&D) sections, due to their vital role in academic, industrial, and military applications [1]. Their applications domains cover search and rescue, reconnaissance, intelligent traffic monitoring, border patrol, disaster monitoring, and fire detection (just to name a few) [2]. Small-scale UAV copters, such as quadcopters and helicopters, have attracted many researchers for their unique characteristics. Quadcopters have Vertical Takeoff and Landing (VTOL) capability and perform different flight missions ranging from hovering to cruising with quite good agility and maneuverability. It is considered an ideal platform for nonlinear control law research and a good test bench for trajectory planning algorithms for both remotely piloted and autonomous missions. Designing and implementing a smallscale UAV quadcopter is considered a challenging job [3], due to its role in reducing the gap between the theoretical studies and practical engineering methodologies. During the implementation, researchers might get stuck with many difficulties such as UAV platform specification, airborne systems, communication links, Ground Control Station (GCS) software capabilities [4], and the multiplexed data logging of different inputs and outputs for the Unmanned Aerial System (UAS). Owing to the advent of Microelectromechanical System (MEMS) technology, the airborne systems are shrinking in size and weight. Moreover, using the Commercial offthe-Shelf (COTS) components, it is possible to develop airborne avionics system for a small-scale UAV quadcopter Hindawi Publishing Corporation rectional GSM communication for both uplink and downlink with latency less than 30...