Challenges of Oral Medications in Patients With Advanced Breast Cancer

Palmieri, Frances M.; Barton, Debra L.

doi:10.1016/j.soncn.2007.10.004

Cited by 26 publications

(25 citation statements)

References 17 publications

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“…For dosing and scheduling, reminders may be recommended [57]. Individuals learn in different ways, and repetition can help reinforce important messages [62]. Oncology nurses can also develop ongoing communications with the women by phone calls, email, or contact with a family member or neighbour, and these communications may improve adherence [61].…”

Section: Nursesmentioning

confidence: 99%

“…The use of reminder systems may improve adherence to oral anti-cancer drugs in breast cancer [62]. Reminder Breast Cancer Res Treat (2011) 129:299-308 305 systems included marked-up calendars, reminder notes, tear-off pads, diaries or record sheets, pill boxes, pill blister packs, telephone reminders, microelectronic monitoring systems and pagers with alarms and text messages [62].…”

Section: Reminders Education Injectionmentioning

confidence: 99%

“…Reminder Breast Cancer Res Treat (2011) 129:299-308 305 systems included marked-up calendars, reminder notes, tear-off pads, diaries or record sheets, pill boxes, pill blister packs, telephone reminders, microelectronic monitoring systems and pagers with alarms and text messages [62]. However, to our knowledge none of these reminder systems have been specifically tested in women using oral anti-cancer drugs.…”

Section: Reminders Education Injectionmentioning

confidence: 99%

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Adherence to oral endocrine treatments in women with breast cancer: can it be improved?

Doggrell

2011

Breast Cancer Res Treat

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There is a perception that women on oral endocrine treatments for oestrogen receptor-positive breast cancer will be adherent to these medicines, as they are facing a serious life-threatening disease, and the oral endocrine treatments are effective, easy to use and generally well tolerated. This is not in fact the case, and this is the basis of the first half of this review. The second half is of whether the changes/interventions to 'improve' adherence do actually increase adherence to the oral endocrine medicines. The review shows that better outcomes are achieved with good adherence to endocrine treatments in breast cancer. The rates of adherence to endocrine treatments range between 15 and 50%, and are influenced by a large number of factors (e.g. adverse effects, lack of belief in treatment, psychological problems and poor patient-health care provider relationship). Interventions to minimise the adverse effects have been used in an attempt to improve the adherence to the endocrine treatment therapies, but it is not known whether these do actually improve adherence. Similar, it has been assumed that interventions by health professionals (doctors, nurses and pharmacists) will improve the adherence, but this has not been tested. In conclusion, in women with breast cancer, we know there is a problem with adherence. There are also many approaches and suggestions about how to improve adherence to the oral endocrine treatments, but none of these approaches/suggestions have been scientifically tested, and they need to be.

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Section: Nursesmentioning

confidence: 99%

Section: Reminders Education Injectionmentioning

confidence: 99%

Section: Reminders Education Injectionmentioning

confidence: 99%

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Adherence to oral endocrine treatments in women with breast cancer: can it be improved?

Doggrell

2011

Breast Cancer Res Treat

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“…[11][12][13][14][15] Data regarding adherence to capecitabine are limited as reported studies have employed very small sample sizes [16][17][18] or have been components of clinical trials which do not reflect usual care 19 and thus have tended to overestimate adherence. 20 There is therefore a clear need for further studies measuring adherence to capecitabine in a naturalistic setting.…”

Section: Introductionmentioning

confidence: 99%

Capecitabine non-adherence: Exploration of magnitude, nature and contributing factors

Bhattacharya

Easthall

Willoughby

et al. 2012

J Oncol Pharm Pract

110

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Adherence to capecitabine is high with a strong conviction that the therapy is necessary. However, concerns were expressed regarding the experience of side effects. Patients have unmet information needs regarding the processes involved with monitoring capecitabine efficacy and determination of therapy duration. Healthcare professionals may therefore wish to consider a greater focus on involving patients in the monitoring of their care with respect to efficacy and planned treatment schedules.

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“…That study qualitatively assessed the effect of CML on patients throughout the course of disease and treatment and found that some patients moved through the psychosocial stages of disease by taking the lead in directing their care, interpreting test results on their own, and developing adaptive behaviors to incorporate medication into their daily routines (Guilhot et al, 2013). These findings highlight the importance of patient-driven care, a concept that is established in other cancers (e.g., breast cancer) (Palmieri & Barton, 2007) and recently has gained attention for CML.…”

Section: Empowerment and The Patient Role In Managing Chronic Myeloidmentioning

confidence: 65%

Patient Empowerment in the Management of Chronic Myeloid Leukemia

Coleman¹

2014

Clinical Journal of Oncology Nursing

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Patient empowerment is a patient-centered approach to care in which healthcare providers nurture patients' innate abilities to self-manage and incorporate patient goals for therapy into the overall management plan. Standard care of chronic myeloid leukemia (CML) requires lifelong medication with oral therapy and regular follow-up. The success of CML treatment, therefore, depends on a high degree of patient involvement and motivation, as well as strong collaboration between patients and healthcare providers. Oncology nurses can support patients with CML from the time of diagnosis to the end of treatment to ensure they maintain high levels of involvement in their care. At the author's center, patients who most actively collaborate with their physicians in treatment decisions take personal responsibility for the quality of their care and show good adherence to treatment. In the current article, the author discusses the potential effect of patient response to cancer diagnosis on clinical outlook and describes strategies in place at the cancer center to ensure that patients diagnosed with CML have the best chance at keeping their cancer under control.

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Challenges of Oral Medications in Patients With Advanced Breast Cancer

Cited by 26 publications

References 17 publications

Adherence to oral endocrine treatments in women with breast cancer: can it be improved?

Adherence to oral endocrine treatments in women with breast cancer: can it be improved?

Capecitabine non-adherence: Exploration of magnitude, nature and contributing factors

Patient Empowerment in the Management of Chronic Myeloid Leukemia

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