2023
DOI: 10.21203/rs.3.rs-2414133/v1
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Chandipura virus nucleoprotein interact with heat shock cognate 71 protein in Neuro-2a cells during replication

Abstract: To complete their lifecycle, viruses interacts with variety of cellular proteins. Identifying host proteins involved in the viral lifecycle is an excellent target for drug. In neuro-2a cells, we employed recombinant Chandipura virus (CHPV) nucleoprotein (N) as bait in a protein pull down assay to see which cellular proteins interact with nucleoprotein. A total of ten proteins interact with the CHPV N protein. Out of ten proteins, heat shock cognate 71 (HSC70) protein was investigated further. In CHPV-infected … Show more

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