Change in ascorbic acid and water content of the liver of garden lizard during ageing and partial hepatectomy

Rao, K.L.; Patnaik, B.K.

doi:10.1016/0531-5565(73)90050-8

Cited by 8 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The garden lizard has been used as a model to study metabolic parameters after being partially hepatectomized in the context of the possible influence of age in the process (Rao and Patnaik, 1971a, 1971b, 1973. These works used short observation periods (24 h), so the authors did not document whether the liver recovered its original size and shape.…”

Section: Liver Regeneration In Reptilesmentioning

confidence: 99%

Liver regeneration observed across the different classes of vertebrates from an evolutionary perspective

Delgado–Coello

2021

Heliyon

View full text Add to dashboard Cite

The liver is a key organ that performs diverse functions such as metabolic processing of nutrients or disposal of dangerous substances (xenobiotics). Accordingly, it seems to be protected by several mechanisms throughout the life of organisms, one of which is compensatory hyperplasia, also known as liver regeneration. This review is a recapitulation of the scientific reports describing the different ways in which the various classes of vertebrates deal with liver injuries, where since mammals have an improved molecular toolkit, exhibit optimized regeneration of the liver compared to lower vertebrates. The main molecules involved in the compensatory process, such as proinflammatory and inhibitory cytokines, are analyzed across vertebrates with an evolutionary perspective. In addition, the possible significance of this mechanism is discussed in the context of the long life span of vertebrates, especially in the case of mammals.

show abstract

Section: Liver Regeneration In Reptilesmentioning

confidence: 99%