Change in character of the estrous cycle and gametogenesis during superovulation induced in rats at different stages of the cycle

Zelenina, N. V.; Kitaev, É. M.; Pimenova, Maria

doi:10.1007/bf00840575

Bull Exp Biol Med

1987

DOI: 10.1007/bf00840575

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Change in character of the estrous cycle and gametogenesis during superovulation induced in rats at different stages of the cycle

N. V. Zelenina¹,

É. M. Kitaev²,

Maria Pimenova³

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2005

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“…studies of superovulation in rats, only a single estrous stage was selected for the time of PMSG injection (e.g., estrus [1,10], metestrus [9] or diestrus [5]). Only a few reports, such as in Zalenina et al [11], have described a comparison of induced ovulation efficiencies in female rats receiving PMSG at various stages of the estrous cycle. Therefore, we investigated the influence of the stage of the estrous cycle at the time of PMSG injection on the number of ovulated eggs obtained from female rats.…”

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Estrous Cycle Stage-Independent Treatment of PMSG and hCG can Induce Superovulation in Adult Wistar-Imamichi Rats

et al. 2005

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The estrous cycle influence on the number of ovulated eggs after injection of pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG) was investigated in 12, 18, and 24 weeks old adult female Wistar-Imamichi (WI) rats. PMSG (150 IU/kg) was injected at metestrus, diestrus, proestrus, or estrus, followed by hCG (75 IU/kg) 55 h later. Ovulation was induced at all ages and stages of the estrous cycle. The number of ovulated eggs was not affected by stage for similarly aged rats, however, the number of ovulated eggs obtained after treatment decreased with age. These results demonstrate that the PMSG/hCG treatment can induce ovulation at any stage of estrous cycle in WI rats and efficient superovulation at 12 weeks of age.

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confidence: 99%

Estrous Cycle Stage-Independent Treatment of PMSG and hCG can Induce Superovulation in Adult Wistar-Imamichi Rats

et al. 2005

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Change in character of the estrous cycle and gametogenesis during superovulation induced in rats at different stages of the cycle

Cited by 1 publication

References 8 publications

Estrous Cycle Stage-Independent Treatment of PMSG and hCG can Induce Superovulation in Adult Wistar-Imamichi Rats

Estrous Cycle Stage-Independent Treatment of PMSG and hCG can Induce Superovulation in Adult Wistar-Imamichi Rats

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