Change in Peak Systolic Velocity of Cavernous Artery in Response to Low Intensity Shock Waves Therapy in Diabetic Polyneuropathy Patients with Erectile Dysfunction: A Randomized Controlled Trial

Abstract

Although several reports have documented the subjective improvement of erectile function after low-intensity extracorporeal shockwave therapy (LI-ESWT) in patients with vasculogenic erectile dysfunction (ED), objective assessment data of penile hemodynamics are lacking. The aim of this research is to detect the Change in peak systolic velocity of cavernous artery in response to low intensity shock waves therapy in diabetic patients with erectile dysfunction. This study is a randomized controlled trial. Overall forty male individuals with mean age (48.6±5.52 years)who have erectile dysfunction after diabetes were equally divided into two separate groups. 1st Group received low intensity extracorporeal shock wave therapy (ESWT). 2nd Group received shame therapy by put head of shock wave while machine is turned off. 1st Group received low intensity extracorporeal shock wave with the following parameters: - 3000 SWs (energy intensity of 0.09mJ/mm2) to each of five different sites of application: three areas along the penile shaft and two areas at the crural level for six weeks as a total period of treatment. Measurements of peak systolic velocity by penile duplex were performed before the treatment and after 3months. There were change in peak systolic velocity of the right and left cavernous arteries were low at baseline, indicating arterial insufficiency. After treatment, PSV significantly in the two groups; however, the post-treatment PSV was significantly higher in the SW group compared to the PFE group (p < 0.001, for both arteries).LIESWT is lead to significant changes in patients suffering from erectile dysfunction after diabetes as evidenced by increase in the peak systolic volume of the both right and left cavernous arteries of the shock wave group.