Changes in Antibiotic Prescription After Tooth Extraction: A Population-Based Study from 2002 to 2018

Choi, Yoon Young; Lee, Kyeong Hee

doi:10.1016/j.identj.2021.01.010

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…13,15,36 Currently, research on antibiotics primarily centers around prescription patterns and influencing factors, [37][38][39] common types of antibiotics used, 2,40,41 analysis of antibiotic resistance 42,43 and epidemic trends of antibiotic prescription. 10,35,[44][45][46] One study discovered that the growth of antibiotic consumption in middle-and low-income areas was significantly higher than that in high-income countries. 9 However, there were few long-term studies on antibiotic prescriptions in in middle-and low-income areas.…”

Section: Introductionmentioning

confidence: 99%

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

Li,

Cui,

Wei

et al. 2023

IDR

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Purpose To explore the prescription patterns and usage trends of antibiotics within primary care institutions located in underdeveloped regions of China from 2017 to 2022. Methods A retrospective analysis of antibiotic prescriptions was conducted from 25 primary care institutions in Guizhou Province during the period of 2017–2022. Antibiotic prescriptions were categorized into appropriate and inappropriate use. Appropriate use is further categorized into preferred medication, and antibiotics can be used or substituted. Inappropriate use is further categorized into unnecessary use, incorrect spectrum of antibiotics and combined use of antibiotics. Factors associated with inappropriate use were investigated using generalized estimation equations. Holt-Winters and SARIMA models were employed to predict the number of inappropriate antibiotic prescriptions as the alternative model. Results A total of 941,924 prescriptions were included, revealing a decreasing trend in both the number and inappropriate rates of antibiotic prescriptions from 2017 to 2022. Diseases of the respiratory system (70.66%) was the most frequent target of antibiotic use, with acute upper respiratory infections of multiple and unspecified sites representing 52.04% of these cases. The most commonly used antibiotics were penicillins (64.44%). Among all prescriptions, inappropriate antibiotic prescriptions reached 66.19%. Physicians aged over 35, holding the title of associate chief physician and possessing more than 11 years of experience were more likely to prescribe antibiotics inappropriately. The phenomenon of inappropriate antibiotic use was commoner among children aged five or younger. By comparing model parameters, it was determined that the SARIMA model outperforms the Holt-Winters model in predicting the number of inappropriate antibiotic prescriptions among primary care institutions. Conclusion The number and inappropriate rates of antibiotic prescriptions in southwest China exhibited a downward trend from 2017 to 2022, but inappropriate prescription remains a serious problem in primary care institutions. Therefore, future efforts should focus on strengthening physician education, training, and clinical practice. Additionally, physicians’ awareness of common misconceptions about inappropriate antibiotic use must be improved, and the prescribing behavior of physicians who fulfill patients’ expectations by prescribing antibiotics needs to be modified.

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Section: Introductionmentioning

confidence: 99%

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

Li,

Cui,

Wei

et al. 2023

IDR

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Necessity of Antibiotic usage after Simple Tooth Extraction in Patient with Healthy Systemic Condition in Herat, Afghanistan

Erfan¹,

Khan²,

Taka³

2023

TODENTJ

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Background/Purpose: Over-intake of antibiotics like amoxicillin, penicillin, ceftriaxone, gentamycin, ampiclox, metronidazole and last but not least, tetracycline is a practical hazard in aid-supported settings such as Afghanistan where not only one can get access to them easily, but also they are generously being prescribed without consideration for necessity or side effects. Prescribing antibiotics after simple tooth extraction has remained a questionable topic in dental academia, especially in the third world countries. Among dental procedures, extraction is the most common procedure for the prescription of antibiotics. This study is aimed to determine the necessity of using antibiotics after simple tooth extraction in people with a normal systemic condition and establish its role in reducing pain and discomfort, swelling, and dry socket. Materials and Methods: This double-blinded RCT study was performed in two dental surgeries; Erfan Specialized Dental Clinic and Mena Oral and Dental Care Centre. In all 237 patients, selected systematically, randomized, tooth extraction was performed following the same protocols and materials before and after tooth extraction. Two types of prescriptions (one with antibiotics and one without antibiotics) were prepared in a box. After tooth extraction participants were asked to pick one prescription by chance. All data were collected and analyzed with the SPSS-25 program. Results: Among all participants 76.37% were female and 23.63% were male. Regarding reasons that led to tooth extraction, 43.04% of teeth were extracted due to profound caries, making it the most common reason followed by periodontitis 14.77% and root remnants 10.55%. Pain and discomfort peaked in the first 10 hours after extraction and gradually decreased up to 48 hours after extraction. Swelling was observed 2.53% more in antibiotic users than 0.42% in those that didn’t take them and the p-value was significant <0.05. There is no obvious difference between antibiotic usage and dry socket formation, and the p-value was not significant (>0.05). Conclusion: Antibiotics are not necessary after simple tooth extractions in patients with a normal systemic condition, even in countries like Afghanistan where patients overuse antibiotics, nor do they have any role in reducing pain, swelling, and dry socket after simple extractions.

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Changes in Antibiotic Prescription After Tooth Extraction: A Population-Based Study from 2002 to 2018

Cited by 2 publications

References 25 publications

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

Necessity of Antibiotic usage after Simple Tooth Extraction in Patient with Healthy Systemic Condition in Herat, Afghanistan

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