Vitamin A (VA) deficiency causes over 600000 deaths per year, mostly of young children or pregnant women. Populations prone to VA deficiency obtain about 82% of their VA from plant sources that are rich in pro-VA carotenoids such as beta-carotene. Orange-fleshed sweet potatoes (OFSP) are an especially good source. We evaluated OFSP carotenoid concentrations, bioaccessibility, and cooking and storage, then used this to estimate the amount of OFSP needed to supply 100% of VA for people at risk for deficiency. The grams/day of OFSP needed to meet VA requirements varies with age and sex, and with the amount of beta-carotene in the OFSP. Amounts ranged from 6 to 33 g/d (0.02 to 0.13 cups/d) for a 3-y-old child with marginal VA status; to 68 to 381 g/d, (0.27 to 1.49 cups/d) for a lactating woman with good status. These are amounts that can be eaten on a daily basis. The amount of OFSP needed to supply the VA requirement to all of the 208