Changes in Body Composition, Muscle Strength, and Fat Distribution Following Kidney Transplantation

Dienemann, Thomas; Ziolkowski, Susan L.; Bender, Shaun; Goral, Simin; Long, Jin; Baker, Joshua F.; Shults, Justine; Zemel, Babette S.; Reese, Peter P.; Wilson, F. Perry; Leonard, Mary B.

doi:10.1053/j.ajkd.2020.11.032

Cited by 21 publications

(21 citation statements)

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“…The scale assesses the patient number's satisfaction with the various margins of antiaging facial and the quality corresponding to the face. Finally, one study evaluated the fat-based vascular component SVF, but the numerical values are lacking and cannot be classified into metaelaboration [ 10 ].…”

Section: Resultsmentioning

confidence: 99%

The Application and Efficacy Evaluation of Autologous Fat Transplantation in Antiaging of the Face: Systematic Review and Meta-Analysis

Zhang²,

Zhang

2022

Journal of Healthcare Engineering

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Objective. To evaluate the therapy of autologous fat fine-grain transplantation in the application of antiaging facial by metaelaboration method. Methods. In Chinese and English databases, such as Wanfang, Weipu, CNKI, PubMed, Cochrane Library, and EMBASE, the literature on the use of autologous fat fines graft in antiaging facial was collected, covering randomized comparative trials, nonrandomized comparative studies, comparative case studies, cohort studies, case reports, and so forth. Meta-analyses were also conducted on complication rates, beauty seeker satisfaction, and one-shot success rates. Results. This study included 23 studies that held metaelaborations, including a total of 2852 beauty seekers. According to metaelaboration, the complication rate was 0.02 (95% CI: 0.01, 0.04), the satisfaction rate of beauty seekers was 0.95 (95% CI: 0.91, 0.97), and the success rate of one injection is 0.79 (95% CI: 0.73, 0.84). Conclusion. Autologous fat fine-grain transplantation is obvious and stable in the use of antiaging facial, and it is necessary to popularize the use in clinical practice.

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Section: Resultsmentioning

confidence: 99%

The Application and Efficacy Evaluation of Autologous Fat Transplantation in Antiaging of the Face: Systematic Review and Meta-Analysis

Zhang²,

Zhang

2022

Journal of Healthcare Engineering

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“…In a recent study by Dienemann et al [ 29 ], muscle mass and strength were improved after kidney transplantation but remained lower than controls and resulted in persistent relative sarcopenia. Several findings in our study are clinically important and might facilitate better decision making in the evaluation of a potential kidney transplant recipient.…”

Section: Discussionmentioning

confidence: 99%

Presence of Sarcopenia before Kidney Transplantation Is Associated with Poor Outcomes

et al. 2022

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Introduction: Kidney transplantation is the treatment of choice for patients with renal failure. It is crucial to select which patients may benefit from renal transplantation and which are at high risk for post-transplant complications. Sarcopenia is associated with poor outcome in various conditions, including in chronic kidney disease patients. The gold standard for measuring sarcopenia is computed tomography (CT) imaging to estimate muscle mass and quality since it is objective, reproducible, and reflects the overall health condition. The data regarding those measurements among kidney transplant recipients are limited, therefore we aimed to describe it in patients before kidney transplantation, assess the parameters associated with sarcopenia, and evaluate the clinical significance of those markers on outcomes following transplantation. Methods: We retrospectively analyzed 183 kidney transplant recipients who had a CT scan 90 days prior to transplant. Sarcopenia was assessed by measuring the cross-sectional area (CSA) and mean muscle density of the psoas muscle at the third and fourth lumbar vertebrae levels and paravertebral muscles at the 12th thoracic vertebra level. Results: There was a strong linear correlation between muscle size measured as CSA of the psoas muscle at the L3 and L4 vertebral body level and the CSA of the paravertebral muscles at the D12 vertebra level, and a moderate correlation to muscle density at those levels. Age was independently associated with risk of sarcopenia, defined as psoas CSA in the lowest tertile, with every year of age increasing the risk by 5%. CSA at the L3 level had a significant independent association with post kidney transplantation mortality, with an adjusted hazard ratio of 0.86 per cm2. There was a significantly longer hospitalization period postoperation in kidney recipients in the lower tertile of psoas CSA and density. Conclusions: Sarcopenia as measured by psoas CSA is associated with poor short- and long-term outcomes following kidney transplantation and should be included as part of the assessment of kidney transplantation candidates.

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“…Previous evidence indicates that other risk factors for weight gain after KT include a younger age, black ethnicity, lower socioeconomic status, diabetes mellitus, acute rejection, steroids, and antidepressants [ 29 ]. Post-transplant weight gain is due to increases in both fat and fat free mass [ 32 ]. However, KT recipients exhibit persistent relative sarcopenia, as the gain in fat mass outpaces the improvements in muscle mass and strength, which remain low when compared to healthy controls [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

“…Post-transplant weight gain is due to increases in both fat and fat free mass [ 32 ]. However, KT recipients exhibit persistent relative sarcopenia, as the gain in fat mass outpaces the improvements in muscle mass and strength, which remain low when compared to healthy controls [ 32 ]. These observations highlight the need for screening KT recipients not only for obesity, but also for altered body composition, this population being at increased risk of sarcopenic obesity [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Obesity and Lifestyle Habits among Kidney Transplant Recipients

et al. 2022

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Background: Obesity may negatively impact clinical outcomes in kidney transplant (KT) recipients. Limited information is available on the prevalence of obesity in this population, and on the lifestyle habits associated with obesity. Methods: we conducted an online, anonymous survey to assess of the proportion of KT recipients with obesity, adherence to the Mediterranean diet (i.e., a dietary regimen with proven renal and cardiovascular outcomes) using the MEDI-Lite questionnaire, and level of physical activity using the International Physical Activity Questionnaire (IPAQ) short form among KT recipients. Results: 255 KT recipients participated. Median (25th–75th quartile) age was 56.0 (48.0; 62.0) years, 43.9% female, median BMI 23.9 (21.6; 26.5) kg/m2. The proportion of KT recipients with obesity was 9.8% (95% confidence interval, 6.4 to 14.1%). Adequate adherence to the Mediterranean diet (Medi-Lite score >9) was overall low (44.7%; 40.0 vs. 45.2% in those with or without obesity, respectively; p = 0.618). In participants with obesity the Medi-Lite score inversely correlated with BMI (R = −0.45; p < 0.025). Overall, 30.6% of participants had a low level of physical activity (44.0 vs. 29.1% of those with or without obesity, respectively; p = 0.125). The amount of energy expended walking was significantly lower among participants with obesity (462 (0.0; 1436) vs. 1056 (433; 2005) METs/week, p = 0.017). Conclusions: the burden of obesity among KT recipients is similar to that of the general population. Adherence to the Mediterranean diet was generally low, and nearly one-third of participants had a low level of physical activity. Building specialized multidisciplinary teams to manage obesity in KT recipients is urgently needed.

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Changes in Body Composition, Muscle Strength, and Fat Distribution Following Kidney Transplantation

Cited by 21 publications

References 50 publications

The Application and Efficacy Evaluation of Autologous Fat Transplantation in Antiaging of the Face: Systematic Review and Meta-Analysis

The Application and Efficacy Evaluation of Autologous Fat Transplantation in Antiaging of the Face: Systematic Review and Meta-Analysis

Presence of Sarcopenia before Kidney Transplantation Is Associated with Poor Outcomes

Obesity and Lifestyle Habits among Kidney Transplant Recipients

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