Changes in Cardiac Parameters of Renal Allograft Recipients: A Compilation of Clinical, Laboratory, and Echocardiographic Observations

Iqbal, Masud; Rashid, HU; Banerjee, Sajal K; Rahman, Md. Hamidur; Mohsin, Minhazul

doi:10.1016/j.transproceed.2008.07.099

Cited by 19 publications

(27 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This was considered to be contrary to Iqbal et al[25] in 2008, who showed that the reduction in BP with correction of anemia and a decreased in creatinine level influenced the improvements in LV parameters. Foley et al[6] reported that after renal transplantation, a 17% increase in LVMI (similar to the degree of regression of hypertrophy found on partial correction of anemia by erythropoietin) occurred.…”

Section: Discussionmentioning

confidence: 73%

Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults

El-Khashab¹,

Mohamed²,

Soliman³

et al. 2016

WJN

View full text Add to dashboard Cite

AIMTo compare the effects of renal transplantation on cardiac functions in children and adults.METHODSOne hundred and ten patients attending the nephrology outpatient clinic were enrolled in this study and were divided into six groups. The first two groups consisted each of 30 renal transplant patients who had a successful renal transplantation more than six months, but less than one year. Group I were less than 18 years and group II were more than 18 years. The third and fourth groups, each were 20 chronic renal failure patients on regular hemodialysis. Again, group III were less than 18 years and group IV were more than 18 years. Group V and VI (The control Groups) consisted each of 5 subjects below and above 18 years of age, respectively with normal kidney functions. All patients were subjected to history and examination. The kidney functions and the hemoglobin were analyzed. After obtaining informed consent, echocardiography was done to all patients.RESULTSThere was a statistically significant improvement (P < 0.0001) in all cardiac parameters. A regression in left ventricular end diastolic volume (LVED) both in children (4.7 ± 0.8 to 4.2 ± 0.5) and in adults (5.9 ± 0.7 to 4.9 ± 0.6) were found. There was a regression in left ventricular end systolic volume (LVES) both in children (3.1 ± 0.6 to 2.4 ± 0.4) and in adults (4.1 ± 0.9 to 3.1 ± 0.5). Fractional shortening improves both in children (32.6 ± 5.3 to 41.7 ± 7.6) and in adults (29.0 ± 6.6 to 36.5 ± 4.1). The improvement in ejection fraction (EF) was higher in children (59.7 ± 7.0 to 71.9 ± 6.1) than in adults (52.0 ± 12.5 to 64.8 ± 5.9). However, this degree of improvement (in children: 12.2 ± 5.1) did not show statistical difference (P-value 0.8), when compared to adults (12.7 ± 9.8).CONCLUSIONAfter renal transplantation cardiac functions and morphology (EF/LVED/LVES) do improve markedly and rapidly in both children and adults.

show abstract

Section: Discussionmentioning

confidence: 73%

Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults

El-Khashab¹,

Mohamed²,

Soliman³

et al. 2016

WJN

View full text Add to dashboard Cite

show abstract

“…The lower level of immunosuppressant drug and sirolimus usage is associated with lower prevalence of diastolic dysfunction and higher LVH regression. 8 , 25 - 28 …”

Section: Discussionmentioning

confidence: 99%

The effect of kidney transplantation on speckled tracking echocardiography findings in patients on hemodialysis

Hamidi¹,

Kojuri²,

Attar³

et al. 2018

J Cardiovasc Thorac Res

View full text Add to dashboard Cite

Introduction: Cardiac dysfunction is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Previous studies have shown that kidney transplantation can reverse some of the gross changes in the myocardial structure such as left ventricular ejection fraction (LVEF) and volumes. Whether kidney transplantation can reverse the subtle and early myocardial changes in ESRD patients who do not suffer from gross alternations in myocardial function is not yet studied. The aim of this study was to answer this question. Methods: We followed 25 patients with ESRD at baseline that all of them had a kidney transplant and were reassessed 1 month after the transplantation. Conventional and speckle tracking echocardiography (STE)was done at baseline and 1 month after kidney transplantation in patients. Results: LV hypertrophy was the most prevalent finding at baseline (58%), followed by diastolic dysfunction (53%). Kidney transplantation significantly improved the ejection fraction (EF) (treatment effect = 4.23 ± 2.06%; P = 0.046) and apical 4-chamber strain (treatment effect = -0.89 ± 0.37%; P = 0.021) in the patients. It also reduced the LV mass index (treatment effect = -73.82 ± 11.6; P < 0.001) and relative wall thickness (treatment effect = -0.056±0.023; P = 0.021). Other variables including global longitudinal strain and diastolic dysfunction were not improved significantly. Conclusion: STE may show early improvements in myocardial function 1 month after renal transplantation.

show abstract

“…Iqbal et al 16 demonstrated early decrease in three months and late one-year decrease in LVEDD and LA diameter, which have been reproduced more recently by Casas-Aparicio et al 17 , who also demonstrated a decrease in these diameters one year after kidney transplantation.…”

Section: Discussionmentioning

confidence: 68%

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Souza¹,

Bezerra²,

Sousa³

et al. 2012

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

Changes in Cardiac Parameters of Renal Allograft Recipients: A Compilation of Clinical, Laboratory, and Echocardiographic Observations

Cited by 19 publications

References 10 publications

Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults

Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults

The effect of kidney transplantation on speckled tracking echocardiography findings in patients on hemodialysis

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Contact Info

Product

Resources

About