2002
DOI: 10.1016/s1047-2797(01)00270-8
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Changes in Cardiovascular Disease Risk Factors among American Indians

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Cited by 90 publications
(54 citation statements)
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“…1 A major contributing factor appears to be the development of an excessive burden of cardiovascular risk factors in North American Aboriginal populations, most notably dramatic increases in the prevalence of diabetes mellitus. [4][5][6][7] Increased rates of other traditional cardiovascular risk factors (e.g., hypertension, obesity and albuminuria) have also been reported. [5][6][7] In addition, novel nontraditional cardiovascular risk factors related to chronic subclinical inflammation (C-reactive protein), adipocyte dysfunction (adiponectin and leptin) and prothrombotic activity (homocysteine) may be further contributing to the burden of vascular disease.…”
mentioning
confidence: 99%
“…1 A major contributing factor appears to be the development of an excessive burden of cardiovascular risk factors in North American Aboriginal populations, most notably dramatic increases in the prevalence of diabetes mellitus. [4][5][6][7] Increased rates of other traditional cardiovascular risk factors (e.g., hypertension, obesity and albuminuria) have also been reported. [5][6][7] In addition, novel nontraditional cardiovascular risk factors related to chronic subclinical inflammation (C-reactive protein), adipocyte dysfunction (adiponectin and leptin) and prothrombotic activity (homocysteine) may be further contributing to the burden of vascular disease.…”
mentioning
confidence: 99%
“…The incidence of chronic disease has increased in US Native American Plains tribes in the last several generations along with a shift away from consumption of traditional foods (Conti, 2008;Taylor et al, 2005;Welty et al, 2002). Dietary interventions and recommendations that include increasing consumption of culturally relevant traditional foods have been promoted (Kattelmann et al, 2009;Holm et al, 2010;Jernigan et al, 2010;Schell and Gallo, 2012;Sinclair et al, 2011;Zephier et al, 1997).…”
Section: Discussionmentioning
confidence: 99%
“…14,15 In addition, heart disease mortality rates for AIAN Ն65 years of age decreased and cerebrovascular mortality rates increased. Although it is tempting to speculate that the lower mortality from diseases of the heart, coupled with a rising prevalence of hypertension, 29 increased the number of AIAN elders at risk for dying of stroke, reasons for this pattern are not clear. Similarly, the increasing trend in mortality from diseases of the heart among middle-aged AIAN compared with the decreasing trend in older AIAN cannot be explained by this study.…”
Section: Discussionmentioning
confidence: 99%
“…Many AIAN may have different access to health care or different risk profiles compared with the IHS service population. Furthermore, marked heterogeneity in CVD risk factors, 29 mortality, 42 and racial misclassification exists among AIAN. 42 The present report cannot provide region-or tribe-specific information.…”
Section: Study Limitationsmentioning
confidence: 99%