Changes in Clinical Profile, Epidemiology and Prognosis of Left-sided Native-valve Infective Endocarditis Without Predisposing Heart Conditions

Castillo, Francisco; Anguita, Manuel; Castillo, Juan Carlos; Ruiz, Manuel Concha; Mesa, Dolores; Lezo, José Suárez de

doi:10.1016/j.rec.2014.12.014

Cited by 14 publications

(10 citation statements)

References 6 publications

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“…In the renal transplant patients, male predominance was less distinct (55%). (ii) While in the general population, most cases of IE occur in patients aged >60 years, the mean age of the affected kidney transplant patients was 45 years, with almost 90% being younger than 60 years at the time of diagnosis of IE. (iii) IE is associated with a preexisting structural cardiac anomaly in about 75% of patients in the general population .…”

Section: Discussionmentioning

confidence: 99%

Infective endocarditis in the setting of renal transplantation: Case report and review of the literature

Agmon

Goldberg

Cohen

et al. 2017

Transplant Infectious Dis

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The potent immunosuppressive drugs used by transplant recipients place them at risk of infections. Data on infective endocarditis (IE) in the setting of renal transplantation (RT) are sparse. We describe a 36-year-old woman referred to a tertiary medical center for evaluation of elevated creatinine levels 1 month after a second RT. Work-up revealed the presence of all four of Duke's criteria: fever, persistent bacteremia, new-onset tricuspid regurgitation, and masses suspected to be vegetation attached to the tricuspid annulus. Symptoms resolved with antibiotic treatment and fluids. Fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) revealed hypermetabolic absorption in the femoral vascular graft that had been used for hemodialysis prior to transplantation. The graft was removed by open surgery, and the patient was discharged home in good condition with continued antibiotic treatment. Review of the literature yielded 73 previously reported cases of IE in renal transplant recipients. Several differences were noted from IE in the general population: lower male predominance, younger age (<60 years), absence in most cases of a preexisting structural cardiac anomaly, and more variable causative pathogens. Our case also highlights the importance of FDG-PET/CT for detecting the source of IE and alerts clinicians to the sometimes unexpected course of the disease in renal transplant recipients.

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Section: Discussionmentioning

confidence: 99%

Infective endocarditis in the setting of renal transplantation: Case report and review of the literature

Agmon

Goldberg

Cohen

et al. 2017

Transplant Infectious Dis

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“…Another known risk factor for IE is structural heart disease (e.g., rheumatic heart disease). However, IE can develop in patients who have no history of structural heart disease (in nearly one in four cases) [9]. A Spanish study reported an increased proportion of IE in patients with undocumented structural heart disease from 2001 to 2013 (compared with 1987 to 2001) [8].…”

Section: Discussionmentioning

confidence: 99%

Metastatic Osteoarticular Infective Endocarditis by Methicillin-sensitive Staphylococcus Aureus

Al-Bayati

Alshami

Al-Azzawi

et al. 2020

Cureus

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“…There is an increasing prevalence of IE involving structurally normal cardiac valves, accounting for 26-43% of native left-sided IE cases [2,18,19]. Sun et al [18] reported the commonest underlying cardiac predisposition was mitral valve prolapse (MVP) followed by normal valves (26%).…”

Section: Structurally Normal Native Cardiac Valvesmentioning

confidence: 99%

The Role of Modern-Era Echocardiography in Identification of Cardiac Risk Factors for Infective Endocarditis

Sedgwick¹,

Scalia²

2018

Advanced Concepts in Endocarditis

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This chapter provides an updated overview of the scientific literature on cardiac pathology predisposing to infective endocarditis and the estimated risk associated with selected lesion-specific abnormalities, in an era of changing epidemiology and advanced echocardiographic imaging. Importantly, with the evolution of modern-era echo, subtle changes in valve structure and function are now easily detectable and a proportion of cases of apparently 'normal' valves involved with IE, may in fact have subtle pre-existing pathological and/or haemodynamic abnormalities. The chapter will have a clinical focus with an aim to provide the Physician with up-to-date and practical information on cardiac risk factor identification for infective endocarditis.

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Changes in Clinical Profile, Epidemiology and Prognosis of Left-sided Native-valve Infective Endocarditis Without Predisposing Heart Conditions

Cited by 14 publications

References 6 publications

Infective endocarditis in the setting of renal transplantation: Case report and review of the literature

Infective endocarditis in the setting of renal transplantation: Case report and review of the literature

Metastatic Osteoarticular Infective Endocarditis by Methicillin-sensitive Staphylococcus Aureus

The Role of Modern-Era Echocardiography in Identification of Cardiac Risk Factors for Infective Endocarditis

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