Changes in colostral and serum IgG content in swine in relation to time

Frenyó, Vilmos László; Pethes, G.; Antal, Tibor; Szabó, Imre

doi:10.1007/bf02278503

Cited by 41 publications

(33 citation statements)

References 15 publications

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“…Immunoglobulin G was higher than IgA and IgM in colostrum on d 0.5, however, by d 4 of lactation, it decreased to 3.1% of its initial concentration. This is similar to a study by Frenyo, Pethes, Antal, and Szabo (1981) that reported a decrease in milk IgG to 3.2% of the initial concentration by d 5 of lactation. The total concentration of IgG and rate of decline were not affected by treatment.…”

Section: Discussionsupporting

confidence: 91%

Beta-1,3-glucan effect on sow antibody production and passive immunisation of progeny

Chau

Collier

Welsh

et al. 2009

Food and Agricultural Immunology

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b-glucans are glucose homopolymers known to modulate immunity. Here, the b-glucan effect on sow antibody production and passive immunisation of neonatal pigs was analysed. Treatments included: (1) corn-soy fed Control group; (2) b-glucan; (3) Actinobacillus pleuropneumoniae (App) vaccination; and (4) b-glucan'App vaccination. Birth and weaning weights were not affected (P 0.05) by treatment. Independent of treatment, IgA, IgG and IgM in colostrum were elevated and declined rapidly. Vaccination against App resulted in an increase (P B0.05) in IgG and IgA specific for App serotypes 1, 5 and 7 in colostrum and milk, and a corresponding increase (PB0.05) in serum in pigs at 4 d of age. However, b-glucan did not enhance specific App antibodies in pig serum. While the dosage used here did not enhance passive immunisation in pigs, b-glucan can be potentially efficacious as an oral adjuvant to enhance immunoglobulin production in response to vaccination.

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Section: Discussionsupporting

confidence: 91%

Beta-1,3-glucan effect on sow antibody production and passive immunisation of progeny

Chau

Collier

Welsh

et al. 2009

Food and Agricultural Immunology

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“…It remains difficult to determine the proportion of the IgG present in plasma at weaning that comes from the colostrum and that depends on IgG half-life. The half-life of IgG in piglet blood was estimated to average 10 to 15 days of age (Curtis and Bourne, 1973;Frenyó et al, 1981;Klobasa et al, 1981). However, those studies did not take into account the variation in blood volume occurring with piglet growth and probably underestimated the IgG half-life value (Rooke and Bland, 2002).…”

Section: Discussionmentioning

confidence: 99%

Influence of colostrum intake on piglet survival and immunity

Devillers

Dividich

Prunier

2011

Animal

229

154

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Colostrum intake from birth to 24 h after the onset of parturition ( T 24 ) was estimated for 526 piglets from 40 litters. Plasma concentrations of immunoglobulin G (IgG), lactate, glucose and cortisol were determined at T 24 for six piglets per litter. Plasma IgG concentration was also assayed at weaning (28 days) on the same piglets. Rectal temperature was measured at T 24 on all piglets. Mortality was recorded until weaning and comparisons were made between piglets that died before weaning and those that were still alive at weaning. The piglets that died before weaning had lower birth weight, lower colostrum intake, lower weight gain between birth and T 24 , and had a lower rectal temperature, higher plasma cortisol concentration and lower plasma IgG and glucose concentrations at T 24 than piglets still alive at weaning. In addition, a higher proportion of piglets that died before weaning had difficulty taking their first breath after birth and were affected by splayleg. Considering all piglets, colostrum intake was positively related to rectal temperature and plasma glucose concentration and negatively related to plasma cortisol concentration at T 24 . Plasma IgG concentration at T 24 was explained by colostrum intake, IgG concentration in the ingested colostrum, birth weight and birth rank (P , 0.0001). Plasma IgG concentration at weaning was related to plasma IgG concentration at T 24 (r 5 0.54; P , 0.0001) and to colostrum intake (r 5 0.32; P , 0.0001). Finally, body weight was explained by colostrum intake, birth weight and age until 6 weeks of age (P , 0.0001). These results show that colostrum intake is the main determinant of piglet survival through provision of energy and immune protection and has potential long-term effects on piglet growth and immunity.

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“…This age was chosen because maximum IgG levels have been observed in nursing piglets between 8 and 12 h of age (Coalson and Lecce, 1973;Frenyo et al, 1981;Klobasa et al, 1981) and maximum blood volumes for day 1 have been reported at 12 h of age (Ramirez, Miller, Ullrey and Hoefer, 1963). This age was chosen because maximum IgG levels have been observed in nursing piglets between 8 and 12 h of age (Coalson and Lecce, 1973;Frenyo et al, 1981;Klobasa et al, 1981) and maximum blood volumes for day 1 have been reported at 12 h of age (Ramirez, Miller, Ullrey and Hoefer, 1963).…”

Section: Blood Samplingmentioning

confidence: 99%

“…THE newborn piglet has limited energy reserves (Elliot and Lodge, 1977;de Passille and Hartsock, 1979) and only very small amounts of circulatory immunoglobulins (Porter, 1969;Frenyo, Pethes, Antal and Szabo, 1981). As well as being the source of energy, colostrum provides piglets with immunoglobulins (Aumaitre and Seve, 1978) which ensure passive systemic immunity.…”

Section: Introductionmentioning

confidence: 99%

“…Absorption of immunoglobulin occurs through intestinal pinocytocis and transport into the lymph and blood (Lecce, 1966;Staley, Jones and Marshall, 1968;Lecce, 1973;Leary and Lecce, 1976). The concentration of immunoglobulins in colostrum decreases during the first 24 h post partum (Bourne, 1969;Frenyo et al, 1981;Milon, Aumaitre, Le Dividich, Franz and Metzger, 1983), so that later-born piglets, or those whose sucking is delayed by 4 h or more, may have lower serum immunoglobulin levels (Coalson and Lecce, 1973;Yaguchi, Murata, Kagota and Namioka, 1980;Klobasa, Werhahn and Butler, 1981). The concentration of immunoglobulins in colostrum decreases during the first 24 h post partum (Bourne, 1969;Frenyo et al, 1981;Milon, Aumaitre, Le Dividich, Franz and Metzger, 1983), so that later-born piglets, or those whose sucking is delayed by 4 h or more, may have lower serum immunoglobulin levels (Coalson and Lecce, 1973;Yaguchi, Murata, Kagota and Namioka, 1980;Klobasa, Werhahn and Butler, 1981).…”

Section: Introductionmentioning

confidence: 99%

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Sucking behaviour and serum immunoglobulin levels in neonatal piglets

1988

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The relationships between the sucking behaviour of newborn piglets during bouts of sucking and their serum immunoglobulin G (IgG) levels at 12 h of age were investigated in 274 Landrace X Yorkshire piglets from 24 second parity Yorkshire sows. Mean IgG level differed between litters but was not related to the number of live-born piglets or the mean birth weight of the litter; in addition, the amount of variation in IgG level within a litter was not related to the number of live-born piglets or the amount of variation in birth weight of the piglets.Within a litter, lower serum IgG levels were found in piglets of birth orders greater than eight and piglets that had a very low frequency of sucking bouts. The piglets that had the higher IgG levels within a litter were those that started to suck sooner, sucked from many teats and won more of their teat disputes. Piglets that were involved in fewer teat disputes within a litter or took a greater proportion of their sucking bouts on anterior teats did not have higher IgG levels. Piglets that died differed from their surviving litter-mates in having lower IgG levels and having lost weight during the first 12 h after birth. Within a litter, IgG levels were not related to 10-day weight gain. However, litters with a lower mean IgG level also had a lower mean 10-day weight gain. It is suggested that a low mean IgG level in a litter reflects or predicts a low milk production by that sow.

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Changes in colostral and serum IgG content in swine in relation to time

Cited by 41 publications

References 15 publications

Beta-1,3-glucan effect on sow antibody production and passive immunisation of progeny

Beta-1,3-glucan effect on sow antibody production and passive immunisation of progeny

Influence of colostrum intake on piglet survival and immunity

Sucking behaviour and serum immunoglobulin levels in neonatal piglets

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