Changes in hair chromium concentrations with increasing distances from hair roots

Hambidge, K. Michael; Franklin, Michael L.; Jacobs, Margaret A.

doi:10.1093/ajcn/25.4.380

Cited by 22 publications

(10 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The possible contribution of the external environment to zinc in hair content after adequate sample washing procedures has been controversial [2,22,35,53]. However, unpublished observations in this laboratory, paralleling studies reported for chromium in hair [12], have demonstrated that the content of zinc in hair is not dependent on the time for which it has been exposed to the external environment in Denver; mean concentrations of zinc in hair for 30 subjects in [48] that levels of zinc in human hair reflect dietary intake of this element.…”

Section: Discussionmentioning

confidence: 66%

“…The initial aim of this investigation was to determine the content of zinc in hair of apparently normal neonates, infants, children, and young adults who were living in Denver, Colorado. This was part of a more extensive evaluation of hair as a potential index of human trace mineral nutritional status [11][12][13]. After processing these initial analytical data, it was apparent that the population included a number of young children with exceptionally low levels of zinc in hair.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Low Levels of Zinc in Hair, Anorexia, Poor Growth, and Hypogeusia in Children

Km¹,

Hambidge²,

Jacobs³

et al. 1972

Pediatr Res

579

168

View full text Add to dashboard Cite

ExtractConcentrations of zinc in hair were determined for 338 apparently normal subjects living in Denver with ages ranging from 0-40 years. Mean concentrations of zinc in hair were: neonates (25) 174 db 8 (1 SEM); 3 months^-years (93) 88 ± 5; 4-17 years (132) 153 ± 5, and 17^0 years (88) 180 ±4. Ten children more than 4 years of age had levels of zinc in hair of less than 70 ppm. Seven of these ten children had a history of poor appetite and eight had heights on or below the 10th percentile; the high incidence of low growth percentiles was not explicable on a familial basis. Taste acuity was tested in six of these children, and five had evidence of obj ective hypogeusia. After supplementing the diet with small quantities of zinc, taste acuity was normalized in each of these children and levels of zinc in hair increased. Speculation

show abstract

Section: Discussionmentioning

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Low Levels of Zinc in Hair, Anorexia, Poor Growth, and Hypogeusia in Children

Km¹,

Hambidge²,

Jacobs³

et al. 1972

Pediatr Res

579

168

View full text Add to dashboard Cite

show abstract

“…It is assumed that H-Cr content may be an indicator of Cr body stores [34,36,[42][43][44]46,50,[53][54][55]60,61], which are supposed to be compromised in the diabetic state. One would then expect that diabetes would strongly influence H-Cr, which would decrease as the disease progresses.…”

Section: Longitudinal Cr Profiles and Cr Metabolic Ratementioning

confidence: 99%

“…Because impaired glucose tolerance was attributed to compromised Cr body stores, estimation of the Cr status in humans has become a most important task. Determination of Cr in blood [2,9,16,25,27,29 -41], hair [2,34,36,[42][43][44][45][46][47][48][49][50][51][52][53][54][55], and sweat [34,42,43,56] was carried out for that purpose. Changes in plasma Cr (P-Cr) in response to glucose challenge were measured, but the results of different research groups were inconsistent [9,15,27,29,36,57].…”

Section: Introductionmentioning

confidence: 99%

“…Hambidge et al [60] found statistically lower H-Cr av content in children with type 1 diabetes mellitus compared with healthy children. Hambidge et al [44] investigated the variation of Cr content in hair sections 1 to 10 cm in length cut at various distances from the scalp (6-30 cm). In a rather inhomogeneous group with respect to the age and sex of the healthy subjects, they found a mean variation of F 40%.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Longitudinal hair chromium profiles of elderly subjects with normal glucose tolerance and type 2 diabetes mellitus

2007

View full text Add to dashboard Cite

Hair sampling for chromium content following Charnley hip arthroplasty

Owen

Meachim

Williams

1976

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

The chromium content of hair has been studied by neutron activation analysis of samples from 62 patients following a Charnley unilateral or bilateral hip arthroplasty by an artificial joint of stainless steel against polyethylene, inserted three to five years previously. The patients lived in the North Wales area of the British Isles. Hair chromium content was also studied in 51 control subjects of similar age to that of the patients, from the same geographical area and often from the patients' own households. Chromium content was recorded as parts per million (ppm) of hair weighed and analyzed in the state received, without preliminary ashing or chemical "washing" of the samples in the laboratory. Fifty of the 51 control subjects showed less than 2 ppm chromium in hair; one showed 2-5 ppm; none showed more than 5 ppm. Fifty-nine of the 62 patients showed less than 2 ppm chromium in hair; three showed 2-5 ppm; none showed more than 5 ppm. Attention is drawn to certain practical aspects when collecting hair samples for chromium analysis. The use and validity of hair sampling as one method of screening for systemic chromium accumulation following implant surgery is discussed. The method may be a useful adjunct to monitoring of chromium levels in blood samples. In this preliminary study, hair sampling has given no evidence of any major risk of systemic chromium accumulation in patients using a Charnley arthroplasty for periods of up to five years; no conclusion can be made concerning periods longer than this. The findings do not exclude systemic reactions of the hypersensitivity type, since this type of reaction could develop to only small amounts of chromium.

show abstract

Changes in hair chromium concentrations with increasing distances from hair roots

Cited by 22 publications

References 7 publications

Low Levels of Zinc in Hair, Anorexia, Poor Growth, and Hypogeusia in Children

Low Levels of Zinc in Hair, Anorexia, Poor Growth, and Hypogeusia in Children

Longitudinal hair chromium profiles of elderly subjects with normal glucose tolerance and type 2 diabetes mellitus

Hair sampling for chromium content following Charnley hip arthroplasty

Contact Info

Product

Resources

About