Changes in hemodynamics of the carotid and middle cerebral arteries before and after endoscopic sympathectomy in patients with palmar hyperhidrosis: preliminary results

Jeng, Jiann‐Shing; Yip, Ping-Keung; Huang, Sheng-Jean; Kao, Ming‐Chien

doi:10.3171/jns.1999.90.3.0463

Cited by 33 publications

(20 citation statements)

References 29 publications

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“…In the present study, no clear evidence was found for a TES-elicited effect on the MCA mean blood flow. However, this is in some conflict with a previous study where an effect on the MCA systolic blood flow velocity was reported (20).…”

Section: Discussioncontrasting

confidence: 96%

“…Neither does direct stimulation of the cervical sympathetic nerves strongly affect the cerebral circulation under normal conditions (18,19). However, this is in some conflict with a previous study where an effect on the MCA systolic blood flow velocity was reported (20). However, this is in some conflict with a previous study where an effect on the MCA systolic blood flow velocity was reported (20).…”

Section: Discussionmentioning

confidence: 77%

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Sympathicotomy affects cutaneous blood flow, temperature, and sympathicus-mediated reflexes

Koskinen

Blomstedt

2008

Acta Neurologica Scandinavica

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Section: Discussioncontrasting

confidence: 96%

Section: Discussionmentioning

confidence: 77%

Sympathicotomy affects cutaneous blood flow, temperature, and sympathicus-mediated reflexes

Koskinen

Blomstedt

2008

Acta Neurologica Scandinavica

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“…For example, stellate ganglion blockade and sympathectomy in patients with palmar hyperhidrosis increased CBF and CBF velocity in the MCA. 25,26 Moreover, in patients with autonomic failure, CBF increased prominently in response to increases in arterial pressure, suggesting an obligatory role of autonomic neural control for intact cerebral autoregulation. 27 Conversely, stellate ganglion blockade did not change vertebral CBF in patients with headache.…”

Section: Steady-state Autoregulationmentioning

confidence: 99%

Autonomic Neural Control of Dynamic Cerebral Autoregulation in Humans

et al. 2002

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Background-The purpose of the present study was to determine the role of autonomic neural control of dynamic cerebral autoregulation in humans. Methods and Results-We measured arterial pressure and cerebral blood flow (CBF) velocity in 12 healthy subjects (aged 29Ϯ6 years) before and after ganglion blockade with trimethaphan. CBF velocity was measured in the middle cerebral artery using transcranial Doppler. The magnitude of spontaneous changes in mean blood pressure and CBF velocity were quantified by spectral analysis. The transfer function gain, phase, and coherence between these variables were estimated to quantify dynamic cerebral autoregulation. After ganglion blockade, systolic and pulse pressure decreased significantly by 13% and 26%, respectively. CBF velocity decreased by 6% (PϽ0.05). In the very low frequency range (0.02 to 0.07 Hz), mean blood pressure variability decreased significantly (by 82%), while CBF velocity variability persisted. Thus, transfer function gain increased by 81%. In addition, the phase lead of CBF velocity to arterial pressure diminished. These changes in transfer function gain and phase persisted despite restoration of arterial pressure by infusion of phenylephrine and normalization of mean blood pressure variability by oscillatory lower body negative pressure. Conclusions-These data suggest that dynamic cerebral autoregulation is altered by ganglion blockade. We speculate that autonomic neural control of the cerebral circulation is tonically active and likely plays a significant role in the regulation of beat-to

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“…In contrast, sympathetic stimulation with physostigmine [39] worsens ischemic outcome by a mechanism that is associated with increases in plasma epinephrine and norepinephrine. In addition, the study of T2 sympathectomy [40], performing measurements 2-4 weeks after intervention, showed increased the blood flow volume, rate and the vascular diameter in the common carotid artery, and the same effects were observed from 5 minutes after performing SGB or HTEA [41]. Accordingly, the neuropreotective effect of HTEA might be associated with the CBF changes after thoracic sympathetic block.…”

Section: Discussionmentioning

confidence: 99%

Role of Continuous High Thoracic Epidural Anesthesia in Hippocampal Apoptosis after Global Cerebral Ischemia in Rats

Huo

Zhang

et al. 2014

Cell Physiol Biochem

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Background: Cervical sympathetic blockade has been found to reduce cerebral vascular resistance and improve focal cerebral ischemia/reperfusion injury. In this study, we tested the hypothesis that the sympathetic blockade of high thoracic epidural anesthesia (HTEA) would reduce hippocampal apoptosis after global cerebral ischemia (GCI) injury. Methods: Fifteen-minute global ischemia was established by 4-vessel occlusion in adult male Wistar rats. And 0.5% bupivacaine or 0.9% saline (20 μl//h) was infused continuously to the thoracic epidural space through the T4-5 intervertebral space from 15 minutes before ischemia to 24 hours or 72 hours after ischemia. Cerebral blood flow (CBF), Mortality, neurodeficit scores (NDS), Nissl and TUNEL staining, hippocampal superoxide dismutase (SOD) activity, malondialdehyde (MDA) concentrations, western blot of poly (ADP-ribose) polymerase (PARP) and immunohistochemical staining (PARP, Bax and Bcl-2) were determined. Results: Both the hyperpefusion and hypoperfusion after reperfusion were improved by HTEA. HTEA decreased the number of apoptotic neurons in cornu ammonis area 1 (CA1), reduced PARP and Bax expressions with a decrease of Bax/Bcl-2 ratio induced by ischemic injury. The upregulation of SOD activity and the downregulation of MDA were obvious in the HTEA group compared with the GCI group. HTEA also improved NDS but not the mortality rate. Conclusion: Our study demonstrated that continuous HTEA attenuates hippocampal apoptosis and a behavioral deficit after global cerebral ischemia, and that these protective effects are associated with the improved microcirculation, reduced oxidative stress and the less activation of PARP.

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Changes in hemodynamics of the carotid and middle cerebral arteries before and after endoscopic sympathectomy in patients with palmar hyperhidrosis: preliminary results

Cited by 33 publications

References 29 publications

Sympathicotomy affects cutaneous blood flow, temperature, and sympathicus-mediated reflexes

Sympathicotomy affects cutaneous blood flow, temperature, and sympathicus-mediated reflexes

Autonomic Neural Control of Dynamic Cerebral Autoregulation in Humans

Role of Continuous High Thoracic Epidural Anesthesia in Hippocampal Apoptosis after Global Cerebral Ischemia in Rats

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