Changes in Insulin Sensitivity in Morbidly Obese Patients &lt;I&gt;with&lt;/I&gt; or &lt;I&gt;without&lt;/I&gt; Metabolic Syndrome after Gastric Bypass

Coppini, Luciana Zuolo; Bertevello, Pedro Luiz; Gama-Rodrigues, Joaquim; Waitzberg, Dan Linetzky

doi:10.1381/096089206778870030

Cited by 16 publications

(10 citation statements)

References 18 publications

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“…Consequently, a reduction in body weight may normalize the metabolic parameters related to metabolic syndrome in most patients [15,17], and may also affect some markers of early atherosclerotic changes such as C-IMT [18]. However, the benefits of weight loss obtained by bariatric surgery, and its association with C-IMT changes, are not well defined in the literature [19].…”

Section: Introductionmentioning

confidence: 99%

Association of Carotid Intima-media Thickness and Cardiovascular Risk Factors in Women Pre- and Post-bariatric Surgery

et al. 2008

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Section: Introductionmentioning

confidence: 99%

Association of Carotid Intima-media Thickness and Cardiovascular Risk Factors in Women Pre- and Post-bariatric Surgery

et al. 2008

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“…This technique is the most recommended and used in Brazil and is considered the gold standard procedure for weight loss surgery (9,11) . Patients submitted to gastric bypass should perform blood tests regularly to control possible deficiencies in vitamins and minerals (51) .…”

Section: Age and Gender May Influence The Results Of Roux-en-y Gastrimentioning

confidence: 99%

AGE AND GENDER MAY INFLUENCE THE RESULTS OF ROUX-EN-Y GASTRIC BYPASS? Metabolic syndrome parameters

Andrade-Silva

Caranti

Sallet³

et al. 2014

Arq. Gastroenterol.

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-Context -Severe obesity affects the body favoring the development of serious diseases, including hypertension, diabetes mellitus, atherosclerosis and non alcoholic fatty liver disease. Bariatric procedures increased in Brazil in the last decade. Objectives -The purpose of this study was to verify if gender and age in date of procedure resulted significant differences in metabolic syndrome parameters after surgery. Methods -The study involved 205 medical records of adult patients undergoing Roux-en-Y gastric bypass, stratified by gender and age groups and followed one year by a multidisciplinary team. Results -It was observed significant decrease in body mass index, fasting glucose and insulin at all ages and both genders. Lipid profile showed significant improvements except high density lipoprotein cholesterol. Ectopic fat in the liver has decreased after 6 months in patients classified with steatosis at baseline. Patients classified as hypertensive blood pressure levels decreased 6 months after surgical intervention. Conclusion -Roux-en-Y gastric bypass proved to be an important tool in remission of metabolic syndrome parameters. The reduction of body mass accompanied to decrease in insulin resistance resulted in lower prevalence of comorbidities associated with obesity. The benefits were similar and extended both genders and all age groups between 18 and 65 years old. HEADINGS -Bariatric surgery. Metabolic syndrome X. Roux-en-Y anastomosis. Fatty liver.

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“…Mattar et al 122 . found a reduction in ATPIII‐defined MetS from 70 to 14% in a series of 70 patients undergoing laparoscopic Roux‐en‐Y gastric bypass, and Coppini et al 123 . demonstrated complete resolution at 1 year.…”

Section: Treatment Of Metabolic Syndromementioning

confidence: 99%

“…Many patients who qualify for bariatric surgery often have MetS. Few studies have specifically examined its impact on MetS, and most were in European cohorts 121 , 122 , 123 , 124 , 125 , 126 . Gazzaruso et al 121 .…”

Section: Treatment Of Metabolic Syndromementioning

confidence: 99%

Metabolic Syndrome: From Global Epidemiology to Individualized Medicine

Batsis

Nieto-Martínez

López-Jiménez

2007

Clin Pharmacol Ther

149

114

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The metabolic syndrome (MetS) encompasses a constellation of metabolic abnormalities that are thought to place patients at higher risk for the development of diabetes and cardiovascular (CV) disease. The underlying pathophysiology is still a point of contention among various professional organizations leading to inconsistencies in the manner in which MetS is defined. Each definition has its advantages and disadvantages. Nonetheless, there is an agreement that insulin resistance and obesity are likely the central contributing factors. Because the prevalence of obesity has been increasing at a frightening rate in the past few decades, MetS represents a major public health problem that should be identified clinically in individual patients. This review describes the changing epidemiology of obesity and of MetS and discusses its importance in CV disease. We outline the existing controversies that surround MetS and discuss the role of lifestyle, pharmacological, surgical, and novel approaches in its management.

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Changes in Insulin Sensitivity in Morbidly Obese Patients <I>with</I> or <I>without</I> Metabolic Syndrome after Gastric Bypass

Cited by 16 publications

References 18 publications

Association of Carotid Intima-media Thickness and Cardiovascular Risk Factors in Women Pre- and Post-bariatric Surgery

Association of Carotid Intima-media Thickness and Cardiovascular Risk Factors in Women Pre- and Post-bariatric Surgery

AGE AND GENDER MAY INFLUENCE THE RESULTS OF ROUX-EN-Y GASTRIC BYPASS? Metabolic syndrome parameters

Metabolic Syndrome: From Global Epidemiology to Individualized Medicine

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