Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%

Hancox, Joanne; Murdoch, Ian; Parmar, Dipak N.

doi:10.1038/sj.eye.6700146

Cited by 41 publications

(37 citation statements)

References 8 publications

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“…The absence of statistically significant differences due to different photoperiods permits us to exclude the influence of the natural papillary light reflex, such as mydriasis and myosis, on the circadian rhythm of IOP. The application of mydriatics resulted in a significant elevation of IOP in cats and humans, probably due to a decrease in aqueous outflow [21,44]. Also, the presence of the acrophase of IOP circadian rhythm during the photophase in the D/L period, effectively excludes the influence of the natural papillary light reflex on IOP circadian rhythm regulation.…”

Section: Discussionmentioning

confidence: 99%

Influence of Different Artificial Lighting Regimes on Intraocular Pressure Circadian Profile in the Dog (<i>Canis familiaris</i>)

et al. 2010

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The present study was undertaken to determine the temporal variation in intraocular pressure (IOP) and if this variation is under circadian clock control. The authors exposed five female and five male Beagles to four different artificial lighting regimes: 12/12 light/dark (L/D) period, 12/12 D/L period, constant light, and constant darkness. IOP was measured at 3 h intervals over a 48-h period. Statistical analysis of the data was performed by multivariate ANOVA, one-way repeated measure ANOVA and by the single cosinor method. Results showed no statistical effect of gender, eye and photoperiod on IOP values. A significant effect of time for each gender and each eye during all lighting regimes was seen, except during constant light, and also robust daily rhythmicity of IOP values in all L/D periods, except during constant light. In conclusion IOP values in the dog show a circadian rhythm and this rhythm is driven by a central pacemaker.

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Section: Discussionmentioning

confidence: 99%

Influence of Different Artificial Lighting Regimes on Intraocular Pressure Circadian Profile in the Dog (<i>Canis familiaris</i>)

et al. 2010

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“…A telemedicine-applicable screening method for adults at risk of macular changes, preceding an evaluation by an ophthalmologist looking for abnormalities in the fovea, is of paramount importance since it would allow catching pathology at an early stage and referring the subject in question for a comprehensive evaluation and further management. Fundus photography combined with fluorescein angiography detects early pathology with great precision; however, such an effort is unrealistic and is associated with rare but serious complications: intravenous fluorescein injection has been reported to cause allergy, anaphylactic shock can lead to possible death [14, 15], and pharmacologic dilatation can result in an acute angle-closure glaucoma attack [16]. A method using modern technology avoiding pupil dilatation and the infusion of systemic dyes would be ideal for screening.…”

Section: Discussionmentioning

confidence: 99%

Comparison between Nonmydriatic Spectral Domain Optical Coherence Tomography and Conventional Ophthalmologic Examination in Detecting Adult Macular Pathology

Mehanna

Fattah

Ghazi³

et al. 2018

Ophthalmologica

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Objective: To compare nonmydriatic spectral domain optical coherence tomography (NMOCT) to comprehensive ophthalmologic evaluation (COE) in detecting adult macular abnormalities. Methods: This is a single-reader observational pilot study of adults older than 50 years with no known ophthalmologic problems to assess the correlation between NMOCT and COE in detecting macular abnormalities classified as epiretinal, intraretinal, subretinal, or a combination thereof. Subjects underwent NMOCT of the macula followed by COE which included a dilated fundus examination and ancillary tests as needed. Results: A total of 771 eyes of 406 patients were included. Cohen’s kappa coefficient of agreement between NMOCT and COE for detecting any abnormality was high (0.90, p < 0.0001), with NMOCT having an overall sensitivity of 82.65% and specificity of 98.97%. Sensitivities and specificities of NMOCT in detecting each category of macular abnormalities were as follows: epiretinal (86.36%, 99.73%), intraretinal (80.00%, 99.58%), and subretinal (88.89%, 99.73%), respectively. Conclusion: NMOCT is a promising tool for detecting adult macular abnormalities.

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“…[1][2][3][4] We describe a case of a pediatric aphakic patient who repeatedly showed a substantial decrease in intraocular pressure after the administration of cycloplegic drops.…”

Section: Case Reportmentioning

confidence: 99%

Dramatic Decrease in Intraocular Pressure Following Topical Administration of Cycloplegics in an Aphakic Child

Salam¹,

Rothman²,

Granet³

et al. 2005

Journal of American Association for Pediatric Ophthalmology and

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Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%

Cited by 41 publications

References 8 publications

Influence of Different Artificial Lighting Regimes on Intraocular Pressure Circadian Profile in the Dog (<i>Canis familiaris</i>)

Influence of Different Artificial Lighting Regimes on Intraocular Pressure Circadian Profile in the Dog (<i>Canis familiaris</i>)

Comparison between Nonmydriatic Spectral Domain Optical Coherence Tomography and Conventional Ophthalmologic Examination in Detecting Adult Macular Pathology

Dramatic Decrease in Intraocular Pressure Following Topical Administration of Cycloplegics in an Aphakic Child

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