1985
DOI: 10.1113/expphysiol.1985.sp002937
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Changes in Intrapulmonary Chemoreceptor Discharge in Response to the Adjustment of Respiratory Pattern During Hyperventilation in Domestic Fowl

Abstract: It has been suggested that avian vagal intrapulmonary CO2‐sensitive receptors (i.p.c.) may be capable of monitoring the rate and extent of CO2 wash‐out from the lung during spontaneous breathing. The purpose of this study was to record i.p.c. discharge activity in spontaneously breathing domestic fowl when minute volume (V1) was elevated from resting levels. This was accomplished by administration of almitrine (2 mg. kg−1 i.v.), a respiratory stimulant drug that has been shown to have a specific long‐lasting s… Show more

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