Changes in life-history traits, antioxidant defense, energy metabolism and molecular outcomes in the cladoceran Daphnia pulex after exposure to polystyrene microplastics

Zhu, Chenxi; Zhang, Tongqing; Liu, Xiaowei; Gu, Xiankun; Li, Daming; Yin, Jiawen; Jiang, Qichen; Zhang, Wenyi

doi:10.1016/j.chemosphere.2022.136066

Cited by 9 publications

(14 citation statements)

References 58 publications

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“…In addition, the levels of TG, TCHO, and GLU were significantly altered after NPs exposure, suggesting that L. vannamei metabolism was also disturbed by NPs consumption. Previous studies have also reported the metabolism-disrupting effect of MPs in other aquatic organisms ( Zhao et al, 2021 ; Zhu et al, 2022 ). The current study showed that NPs not only altered the composition of intestinal microbial species in L. vannamei , but also damaged the intestine and caused changes in metabolic and immune system-related proteins.…”

Section: Discussionmentioning

confidence: 95%

Effects of nanoplastics on the gut microbiota of Pacific white shrimp Litopenaeus vannamei

Zhu,

Li,

Liu

et al. 2024

PeerJ

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Nanoplastics (NPs) are an abundant, long-lasting, and widespread type of environmental pollution that is of increasing concern because of the serious threats they might pose to ecosystems and species. Identifying the ecological effects of plastic pollution requires understanding the effects of NPs on aquatic organisms. Here, we used the Pacific white shrimp (Litopenaeus vannamei) as a model species to investigate whether ingestion of polystyrene NPs affects gut microbes and leads to metabolic changes in L. vannamei. The abundance of Proteobacteria increased and that of Bacteroidota decreased after NPs treatment. Specifically, Vibrio spp., photobacterium spp., Xanthomarina spp., and Acinetobacter spp. increased in abundance, whereas Sulfitobacter spp. and Pseudoalteromonas spp. decreased. Histological observations showed that L. vannamei exposed to NP displayed a significantly lower intestinal fold height and damaged intestinal structures compared with the control group. Exposure to NPs also stimulated alkaline phosphatase, lysozyme, and acid phosphatase activity, resulting in an immune response in L. vannamei. In addition, the content of triglycerides, total cholesterol, and glucose were significantly altered after NP exposure. These results provided significant ecotoxicological data that can be used to better understand the biological fate and effects of NPs in L. vannamei.

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Section: Discussionmentioning

confidence: 95%

Effects of nanoplastics on the gut microbiota of Pacific white shrimp Litopenaeus vannamei

Zhu,

Li,

Liu

et al. 2024

PeerJ

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“…The escalating severity of microplastic pollution in estuaries has aroused considerable concern due to its adverse effects on immune responses, glucose and lipid metabolism, and ion transport in aquatic animals, such as zebrafish, Daphnia pulex and Macrobrachium nipponense. 5,21,22 The mitochondrial respiratory chain serves as a cellular powerhouse, generating substantial quantities of ATP via beta-oxidation and the tricarboxylic acid cycle. 17,18 Copper ions constitute the active center of respiratory chain complex IV, also known as cytochrome C oxidase.…”

Section: Discussionmentioning

confidence: 99%

Metal ion transport: unveiling the difference of nanoplastics and microplastics in Chiromantes dehaani glucolipid metabolism

Han,

Yang,

Zhou

et al. 2024

Environ. Sci.: Nano

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“…Furthermore, the use of more sophisticated proteomics techniques allowed the identification and quantification of the proteins affected by the chronic exposure of water flea D. pulex neonates to 1 mg/L of 500 nm PS MPs, showing an activation of DNA repair and transcription (upregulated proteins: U6 snRNA-associated Sm-like protein LSm3 and LSm4, helicase SWR1, and DNA excision repair protein ERCC6), and an inhibition of lipid metabolism and response to unfolded or misfolded proteins (e.g., regulation of glucose metabolic process, very long-chain fatty acid catabolic process, positive regulation of fatty acid oxidation, IRE1-mediated unfolded protein response, and protein quality control for misfolded or incompletely synthesized proteins) [92]. The same model organism was used to investigate the effects of PS NPs (1 mg/L) in the nano-size range (average size 70 nm) after 21 days of exposure.…”

Section: Effects Of Ps Mnps On the Proteome Of Aquatic Invertebratesmentioning

confidence: 99%

Polystyrene Micro- and Nanoplastics (PS MNPs): A Review of Recent Advances in the Use of -Omics in PS MNP Toxicity Studies on Aquatic Organisms

Eliso,

Billè,

Cappello

et al. 2024

Fishes

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In recent years, micro- and nanoplastics (MNPs) have represented an emerging threat for the aquatic environment due to their persistence and widespread distribution. Indeed, their small size and increased surface area lead to a high biological reactivity, which can be crucial for the health status of biota. To date, several studies have investigated lethal and sublethal endpoints of MNPs, while one of the main challenges is to understand their mechanisms of toxicity in a comprehensive manner. With this aim, the field of aquatic ecotoxicology can now benefit from the -omics approaches. This review focuses on the recent advances related to the use of transcriptomics, proteomics, and metabolomics to deeply investigate the molecular and biochemical responses of aquatic organisms, both fishes and aquatic invertebrates, to pristine polystyrene (PS) MNPs. The literature reviewed revealed that transcriptomics and metabolomics are the most frequently used -omic approaches. Overall, the studies taken into consideration shed light on the events triggered by PS MNPs at molecular and cellular levels, identifying as mechanisms of toxicity the pathways involved in oxidative stress, energy metabolism, immune response, and the nervous system. Future studies should therefore focus on the use and integration of multi-omics approaches for a more comprehensive understanding of the mechanisms involved in MNPs toxicity.

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Changes in life-history traits, antioxidant defense, energy metabolism and molecular outcomes in the cladoceran Daphnia pulex after exposure to polystyrene microplastics

Cited by 9 publications

References 58 publications

Effects of nanoplastics on the gut microbiota of Pacific white shrimp Litopenaeus vannamei

Effects of nanoplastics on the gut microbiota of Pacific white shrimp Litopenaeus vannamei

Metal ion transport: unveiling the difference of nanoplastics and microplastics in Chiromantes dehaani glucolipid metabolism

Polystyrene Micro- and Nanoplastics (PS MNPs): A Review of Recent Advances in the Use of -Omics in PS MNP Toxicity Studies on Aquatic Organisms

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