“… 14 , 15 , 16 However, the results were controversial because of the variety of demographic characteristics (eg, age, sex), evaluation methods, biomechanics of the orthodontic treatment, and characteristics of the PE group. Most previous studies reported that premolar extraction did not affect M3 angulation measured by either M3–M2 angle 17 , 18 , 19 , 20 or M3–occlusal plane (M3–OP) angle. 17 , 19 Contrarily, M3–M2 angle, 21 M3–horizontal plane (M3–HP), 22 and M3 eruption space 17 , 19 , 23 were found to improve in studies with carefully selected orthodontic cases.…”