2012
DOI: 10.1016/j.jss.2011.11.692
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Changes in Morphology and Function in Small Intestinal Mucosa After Roux-en-Y Surgery in a Rat Model

Abstract: Background-Currently there is no an appropriate model to study intestinal mucosal atrophy in vivo that preserves the nutritional status of the organism.

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“…Accordingly, both immunological and barrier function appear to be impaired with enteral starvation. Animal studies suggest that also physical interaction with luminal chyme because of gut motility plays a role in preservation of integrity and function of the gut mucosa [38][39][40]. At the same time, enteral stimulus is needed to activate intestinal motor activity [41], and to maintain physiological interaction of commensal bacteria with enteric immune cells [42].…”
Section: Beneficial Effects Of Enteral Nutritionmentioning
confidence: 99%
“…Accordingly, both immunological and barrier function appear to be impaired with enteral starvation. Animal studies suggest that also physical interaction with luminal chyme because of gut motility plays a role in preservation of integrity and function of the gut mucosa [38][39][40]. At the same time, enteral stimulus is needed to activate intestinal motor activity [41], and to maintain physiological interaction of commensal bacteria with enteric immune cells [42].…”
Section: Beneficial Effects Of Enteral Nutritionmentioning
confidence: 99%