Changes in NADH-Ubiquinone Reductase (Complex I) with Autolysis in the Rat Heart as Experimental Model

Abstract

Complex I (NADH-ubiquinone reductase) is a complex system located in the inner mitochondrial membrane and has the ability to catalyse several different enzymatic reactions concerned in electron transport. It is known to be one of the first components of the respiratory chain to be damaged by ischemia. Our results, using autolysis in the rat heart as experimental model, indicate that the NADH dehydrogenase system was impaired relatively early during ischemia while transhydrogenation and NADPH dehydrogenation appeared to be relatively resistant.

The relationship between coenzyme Q10 level and diastolic dysfunction in coronary artery disease patients with preserved left ventricular systolic function

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In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3)

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Impact of the mean platelet volume level on clinical outcomes in outpatient patients with pulmonary arterial hypertension

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