Changes in nutritional status in childhood cancer patients: A prospective cohort study

Brinksma, Aeltsje; Roodbol, Petrie F.; Sulkers, Esther; Kamps, Willem A.; Bont, Eveline S.J.M. de; Boot, Annemieke M.; Burgerhof, Johannes G. M.; Tamminga, R. Y. J.; Tissing, Wim J. E.

doi:10.1016/j.clnu.2014.01.013

Cited by 89 publications

(132 citation statements)

References 33 publications

Supporting

Mentioning

111

Contrasting

Unclassified

Order By: Relevance

“…The consequences of malnourishment during therapy for paediatric cancer may be related to altered immune function24 (eg, delayed recovery of absolute neutrophil count) and include decreased tolerance to chemotherapy,25 greater severity of complications, and increased relapse rates,26 which subsequently increase the length of hospital stay. In addition, malnourishment is associated with hospital-acquired infections among paediatric cancer patients,4 which also increases the length of stay 19.…”

Section: Discussionmentioning

confidence: 99%

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Conner

Avilés-Robles

Asdahl

et al. 2016

BMJ Support Palliat Care

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Conner

Avilés-Robles

Asdahl

et al. 2016

BMJ Support Palliat Care

View full text Add to dashboard Cite

show abstract

“…This tool has not been designed to identify subjects who are at risk of developing obesity during cancer treatment. Although the development of obesity is considered a concern for children undergoing treatment for cancer [1,3] and proper education should occur to prevent obesity from developing, it is not considered an acute nutrition priority requiring prompt nutrition intervention during cancer treatment in children.…”

Section: Aj Murphy Et Al / Clinical Nutrition XXX (2015) 1e6mentioning

confidence: 99%

Evaluation of the nutrition screening tool for childhood cancer (SCAN)

et al. 2016

View full text Add to dashboard Cite

s u m m a r yBackground & aims: Malnutrition is a serious concern for children with cancer and nutrition screening may offer a simple alternative to nutrition assessment for identifying children with cancer who are at risk of malnutrition. The present paper aimed to evaluate the nutrition screening tool for childhood cancer (SCAN). Methods: SCAN was developed after an extensive review of currently available tools and published screening recommendation, consideration of pediatric oncology nutrition guidelines, piloting questions, and consulting with members of International Pediatric Oncology Nutrition Group. In Study 1, the accuracy and validity of SCAN against pediatric subjective global nutrition assessment (pediatric SGNA) was determined. In Study 2, subjects were classified as 'at risk of malnutrition' and 'not at risk of malnutrition' according to SCAN and measures of height, weight, body mass index (BMI) and body composition were compared between the groups. Results: The validation of SCAN against pediatric SGNA showed SCAN had 'excellent' accuracy (0.90, 95% CI 0.78e1.00; p < 0.001), 100% sensitivity, 39% specificity, 56% positive predictive value and 100% negative predictive value. When subjects in Study 2 were classified into 'at risk of malnutrition' and 'not at risk of malnutrition' according to SCAN, the 'at risk of malnutrition' group had significantly lower values for weight Z score (p ¼ 0.001), BMI Z score (p ¼ 0.001) and fat mass index (FMI) (p ¼ 0.04), than the 'not at risk of malnutrition' group. Conclusions: This study shows that SCAN is a simple, quick and valid tool which can be used to identify children with cancer who are at risk of malnutrition.

show abstract

“…These trends are seen in pediatric solid tumor and brain tumor patients as well, but the data on weight gain during treatment appears to be somewhat tumor type specific. A cohort of 133 newly diagnosed patients including brain and solid tumor patients showed increased BMI and fat mass within three months of and doubled by 12 months post diagnosis (21). In contrast, weight loss occurred in 37% of 468 patients with intermediate rhabdomyosarcoma, and low baseline BMI correlated with borderline inferior survival (22).…”

Section: Diet – Calories Versus Compositionmentioning

confidence: 99%

Diet and exercise interventions for pediatric cancer patients during therapy: tipping the scales for better outcomes

2017

View full text Add to dashboard Cite

Obesity at diagnosis is a negative prognostic indicator for several pediatric cancers including acute leukemia and bone tumors. Incidence of obesity in children has increased three fold over the past 2 decades and causes for this include poor diet, excessive caloric intake and lack of physical activity which collectively are referred to as energy balance related behaviors. Few energy balance interventions have been implemented in pediatric cancer patients during treatment, and here we will probe the rationale for pursuing such studies. The need to modify composition of calories consumed and identify specific beneficial exercise regimens will be discussed, relative to weight reduction or management.

show abstract

Changes in nutritional status in childhood cancer patients: A prospective cohort study

Cited by 89 publications

References 33 publications

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Malnourishment and length of hospital stay among paediatric cancer patients with febrile neutropaenia: a developing country perspective

Evaluation of the nutrition screening tool for childhood cancer (SCAN)

Diet and exercise interventions for pediatric cancer patients during therapy: tipping the scales for better outcomes

Contact Info

Product

Resources

About