“…8,41,45,46,[52][53][54][55][56][57][58] These studies revealed a shift in hepatitis A incidence among young age groups and an increasing in the number of symptomatic cases among adolescents and adults in Jordan, Saudi Arabia, Egypt, Kuwait, Algeria, Iran, and Turkey. 8,41,45,46,53,53,54,57,57,58 The global changing pattern observed during these past years urged the introduction of the vaccination against HAV in many part of the world and that to reduce the occurrence of severe symptomatic cases and outbreaks. In Tunisia, HAV vaccination was recently introduced in the National program of immunization to limit the number of susceptible.…”